Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient’s survival most likely resulted from a variety of factors: early identification and treatment, use of a combination of antimicrobial agents (including miltefosine), and management of elevated intracranial pressure based on the principles of traumatic brain injury.
Successful Treatment of an Adolescent With Naegleria fowleri Primary Amebic Meningoencephalitis
FINANCIAL DISCLOSURE: All authors have indicated they have no financial relationships relevant to this article to disclose.
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W. Matthew Linam, Mubbasheer Ahmed, Jennifer R. Cope, Craig Chu, Govinda S. Visvesvara, Alexandre J. da Silva, Yvonne Qvarnstrom, Jerril Green; Successful Treatment of an Adolescent With Naegleria fowleri Primary Amebic Meningoencephalitis. Pediatrics March 2015; 135 (3): e744–e748. 10.1542/peds.2014-2292
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