To examine the associations of asthma symptoms and adolescents’ behaviors/characteristics and their effects on health-related quality of life (HRQoL).

The sample analysis included 7063 adolescents, aged 12 to 17 years, who participated in the NHANES Survey in the United States.

Data were collected from 2001 to 2010 NHANES. HRQoL measures included self-rated health, physically and mentally unhealthy days, and activity limitation days. Asthma was classified as never having asthma, having asthma without symptoms, and having asthma with symptoms. Demographics, risk behaviors (eg, smoking, physical activity), BMI, and health insurance coverage were also factored. Corresponding percentages, prevalence ratios (PRs), and predicted days of the domains of HRQoL by the asthma categories were estimated.

Approximately 6.2% of adolescents reported having asthma without symptoms and 12.4% reported having asthma with symptoms. Adolescents with asthma and symptoms reported significantly worse self-rated health (13.58% vs 7.54% for fair or poor health), more physically unhealthy days...

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