To assess the prevalence of immunoglobulin E–mediated peanut allergy to airborne peanut protein and quantify the peanut protein present in the surrounding air.

A total of 84 peanut-allergic children referred to an airborne peanut challenge at Sachs’ Children and Youths Hospital were included. The majority (74%) had a history of an allergic reaction to peanut; 26% had positive test results, with no reaction history.

This was a retrospective case series. Children underwent an airborne challenge to either roasted peanuts or dry roasted peanuts 50 cm in distance away, with 30 minutes exposure time, followed by 1 hour observation postexposure. Patients were examined at baseline and every 10 minutes during the challenge. Electrostatic filter devices were used to collect aerosolized peanut protein and protein was detected by using the enzyme-linked immunosorbent assay. Measured amounts in air samples were used with confirmed peanut-allergic patients’ serum for basophil activation tests to assess in...

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