In this issue of Pediatrics, Lampe et al1 leveraged data from the National HIV Surveillance System to evaluate trends of annual perinatal HIV diagnoses per 100 000 live births and rates of perinatal HIV transmission events among infants born to women with diagnosed HIV in United States. This allowed the assessment of progress toward achievement of the CDC’s perinatal HIV transmission elimination targets almost a decade after they were established. The authors demonstrate remarkable declines in these rates from 2010, with achievement of both elimination benchmarks in 2019 of fewer than 1 case of perinatal HIV diagnosed per 100 000 live births and a transmission rate of less than 1%. These laudable accomplishments have been made possible through the decades-long coordinated multidisciplinary and multisectoral efforts of HIV research, public health agencies, and advocacy communities. These efforts serve as a model of evidenced-based science leading to effective health and policy...
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