This volume is a transcription of the fourth of an interesting series of conferences on physiology of prematurity sponsored in the past few years by the Josiah Macy, Jr. Foundation. The present volume contains discussions of the following topics: heat regulations; hypothermia and asphyxia of the newborn; chemical structure, functional integration and renal regulation as factors in the physiology of the newborn. An outstanding group of participants presented papers on these topics and discussed the current research in these fields.

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