In a recent review article by Dr. T. E. Cone, Jr., (Pediatrics,43:290, 1969), the author referred to Familial Mediterranean Fever as an example of one of the periodic fevers.

The early descriptions of this disease referred to it as a "periodic disease." However, more comprehensive studies from 1955 to the present clearly indicate that this disease is characterized by episodes of irregular (non-periodic) recurrent attacks of fever and serositis. Thus, the reference to Familial Mediterranean Fever as a periodic disease is misleading.

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