The articles by Liggins and Howie and Baden, et al. in this issue of Pediatrics are of great interest to perinatologists because they describe efforts to extend to premature infants results of recent studies on maturation of lungs of lambs and rabbits in the prevention of hyaline membrane disease. The two reports provide both promise and caution. When labor can be delayed at least 24 hours in infants under 32 weeks, infusion of betamethasone into the mother can prevent respiratory distress in the infant. Results in infants over 32 weeks' gestation suggest a positive benefit, but the number of infants in the series was too small to reach statistical significance.

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