Seeger and Stiehm should be congratulated on their recent careful review of a complex subject, T and B lymphocyte subpopulations.1 They correctly point out the technical problems in the identification of these cell types as well as their significance in the evaluation of certain immunological disorders. In their discussion of T-cell leukemia, however, the authors make the point that T-cell malignancies may be more frequent in younger children, on the basis of a review of lymphoid cell subpopulations by Kersey et al.2

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