Based on statistical analysis of data in 186 children, a formula was derived which allows accurate estimation of glomerular filtration rate (GFR) from plasma creatinine and body length (GFR (ml/min/1.73 sq m) = 0.55 length (cm)/Pcr (mg/dl). Its application to clearance data in a separate group of 223 children reveals excellent agreement with GFR estimated by the Ccr (r = .935) or Cin (r = .905). This formula should be useful for adjusting dosages of drugs excreted by the kidney and detecting significant changes in renal function.
A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine
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G. J. Schwartz, G. B. Haycock, C. M. Edelmann, Adrian Spitzer; A Simple Estimate of Glomerular Filtration Rate in Children Derived From Body Length and Plasma Creatinine. Pediatrics August 1976; 58 (2): 259–263. 10.1542/peds.58.2.259
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