Reports about the response of arthritis associated with agammaglobulinemia to conventional amounts of exogenous γ-globulin have been controversial.1-3 It appears from some of these reports3 that more intensive therapy with exogenous γ-globulin is required for accomplishing remission of joint symptoms that is necessary for control of infections. Pabst and Gelpke (Pediatrics 61:306, 1978) suggested that a certain level of serum IgG should be achieved and maintained for remission. We report similar results in one of our patients with arthritis and congenital agammaglobulinemia.
Control of Arthritis Associated with Congenital Agammaglobulinemia by High Doses of Exogenous Gamma Globulin
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Rayasam V.S.K. Prasad, Hemant H. Kesarwala, Photini S. Papageorgiou; Control of Arthritis Associated with Congenital Agammaglobulinemia by High Doses of Exogenous Gamma Globulin. Pediatrics August 1980; 66 (2): 327–328. 10.1542/peds.66.2.327a
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