Readers may remember Holtzman's commentary "Hyperlipidemia Screening: A Search for Heffalumps" in the August 1979 issue (Pediatrics 64:270, 1979). Dr Holtzman questioned whether the data supported attempts by pediatricians to screen for and prevent coronary artery disease, except in those with a very strong family history. He questioned "... whether those at risk will benefit from learning of the high probability that they will develop coronary disease or from diet modification...." Dr Glueck, supported by some of our reviewers, took exception at this point and wrote the commentary which follows. We gave Dr Holtzman an opportunity to respond, and his second commentary follows that of Glueck.

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