Blindness due to optic neuritis or panretinopathy has been reported as an acute complication of natural measles infection.5 Recently, loss of visual acuity following measles, mumps, and rubella (MMR) vaccination with the fundoscopic changes of optic neuritis has been described.6 We have observed a child with blindness due to diffuse neuroretinitis temporally associated with measles, mumps, and rubella vaccination and the development of a postvaccination measles syndrome.


A 16-month-old baby girl presented with acute loss of vision 16 days after routine measles, mumps, and rubella vaccination.

The infant had been previously healthy and developmentally normal. She had received three previous oral polio and diphtheria, tetanus, and pertussis vaccinations without adverse reactions.

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