To the Editor.—

We read with interest the report by Syrogiannopoulos et al.1 The authors have reported six cases of isolated septic arthritis and eight cases of osteomyelitis, two with septic arthritis, in children with sickle cell disease. Whereas Salmonella was the commonest cause of osteomyelitis, Streptococcus pneumoniae was the commonest cause of septic arthritis. This appears to be the first report describing several cases of isolated septic arthritis in children with sickle cell disease.

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