In 2021, Kuzniewicz et al1 reported that the difference (Δ-total serum bilirubin [TSB]) between last TSB before discharge and the 2004 American Academy of Pediatrics (AAP) phototherapy threshold was an excellent predictor of a postdischarge TSB above the 2004 AAP phototherapy threshold (area under the receiver operating characteristic curve = 0.93). The 2004 AAP hyperbilirubinemia guidelines have since been updated with thresholds for phototherapy that now increase with each week of gestation and are about 1 to 3 mg/dL higher than those from 2004. We sought to quantify how well the predischarge Δ-TSB predicts a postdischarge TSB exceeding the new 2022 AAP phototherapy thresholds.2 

This retrospective cohort study used the same cohort as our 2021 publication: 163 930 infants born at ≥35 weeks’ gestation July 1, 2012, to December 31, 2017, at 11 Kaiser Permanente Northern California hospitals employing universal TSB screening with at least 1 predischarge TSB....

You do not currently have access to this content.