An error occurred in the article by Pastor-Villaescusa et al, titled “Metformin for Obesity in Prepubertal and Pubertal Children: A Randomized Controlled Trial” published in the July 2017 issue of Pediatrics (2017;140(1): e20164285; http://pediatrics.aappublications.org/content/140/1/e20164285).
On page 1, in the Conclusions section of the Abstract, this reads: “Metformin decreased the BMI z score and improved inflammatory and cardiovascular-related obesity parameters in prepubertal children but not in pubertal children. Hence, the differential response according to puberty might be related to the dose of metformin per kilogram of weight. Further investigations are necessary.” This should have read: “Metformin decreased the BMI z score and improved inflammatory and cardiovascular-related obesity parameters only in prepubertal children, but a differential effect of metformin was not observed in prepubertal compared to pubertal children. Nevertheless, the doses per kilogram of weight administrated may have had an impact on the metformin effect. Further investigations are necessary.”