Errors occurred in the article by Harrington WE et al titled “Vaccine Oka Varicella Meningitis in Two Adolescents” published in the December 2019 issue of Pediatrics (2019;144(6): e20191522. doi:10.1542/peds.2019-1522).
On page 1, in the Abstract, the third sentence read, “Previous cases of reactivated vOka resulting in meningitis have been described in young children who received a single dose of varicella vaccine; less is known about vOka reactivation in older children after the 2-dose vaccine series.”
This should have read, “All but one previously reported cases of reactivated vOka resulting in meningitis have been described in young children who received a single dose of varicella vaccine; less is known about vOka reactivation in older children after the 2-dose vaccine series.”
On page 1, in the introduction, the last two sentences read, “Previous reported cases of vOka meningitis or encephalitis are restricted to individuals who received a single dose of varicella vaccine during childhood.3,4,13–20 We describe vOka varicella meningitis in 2 adolescents, 1 immunocompetent and 1 immunocompromised, both of whom received 2 doses of varicella vaccine as children.”
This should have read, “All3,4,13–20 but one21 previously reported cases of vOka meningitis or encephalitis occurred in individuals who received a single dose of varicella vaccine during childhood. We describe vOka varicella meningitis in an additional 2 adolescents who received 2 doses of vOka as children, 1 immunocompetent and 1 immunocompromised.”
On page 3, in the Discussion, the first sentence read, “To the best of our knowledge, these are the first cases of vOka meningitis described in adolescent patients who received 2 doses of varicella vaccine. These cases suggest that despite the robust immunity induced by a 2-dose series, vOka may reactivate in both immunocompetent and immunocompromised hosts.”
This should have read, “Our 2 cases of vOka meningitis amplify a prior single case report21 and confirm that despite the expected robust immunity induced by a 2-dose series, vOka may reactivate in both immunocompetent and immunocompromised hosts.”
On page 3, in the Discussion, the first full sentence in column 3 read, “Six healthy children between 3 and 12 years of age developed a zoster-like rash before developing neurologic complaints.3,14–17,19,20 All had received 1 dose of varicella vaccine around 1 year of age. The interval between vaccination and presentation with zoster-associated meningitis was 20 months to 11 years.”
This should have read, “Seven healthy children between 3 and 14 years of age developed a zoster-like rash before developing neurologic complaints.3,14–17,19–21 All but one21 had received 1 dose of varicella vaccine around 1 year of age. The interval between vaccination and presentation with zoster-associated meningitis was 20 months to 11 years in those who had received single dose. The one child who had received 2 doses of vaccine at 18 months and at 12 years of age presented 2 years after the second dose.”
On page 5, in the References, a new reference 21 was added. The new reference reads as follows: 21. Chen Y-C, James A, Kung E, Madhavan V. A case of herpes zoster and meningitis in a twice-vaccinated healthy adolescent. J Pediatr Infect Dis. 2017;12:142–144
The original references 21–23 were renumbered as references 22–24 in this section and throughout the article.
The above corrections have been made to the online article.
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