In recent years, we have witnessed a dangerous trend of transphobia and prejudice toward transgender and gender diverse (TGD) children. In 2023 alone, >495 anti-lesbian, gay, bisexual, transgender, queer or questioning bills have been introduced, many of which have passed into law.1 These legislative efforts operate under the guise of protecting children. In reality, they punish caregivers and physicians when they choose to support children. They deny children access to routine health care that has been shown to decrease dramatically high rates of suicide and depression for TGD youth.2,3 They fuel discriminatory rhetoric, which negatively impacts the mental health of TGD children and imperils their safety.4
This article has 2 main aims:
to refute the idea that gender-affirming care (GAC) is child maltreatment; and
to demonstrate how withholding GAC is harmful to children and amounts to state-sanctioned medical neglect and emotional abuse.
Gender Identity and Gender-Affirming Care
Gender identity is one’s internal sense of self and can be binary, including transgender and cisgender identities, nonbinary and gender expansive, and not exclusively masculine or feminine.4 Gender dysphoria (GD) is the distress resulting from incongruence between one’s assigned sex at birth and gender identity; not all TGD individuals experience GD. Gender diversity is a normal part of child development.2 GAC entails a patient-centered approach that supports individuals in living their authentic gender identities, whether they exist on the binary or outside of it. Although some individuals make it seem that GAC is a new, experimental area of medicine, GAC is evidence-based. Furthermore, most TGD youth do not receive any medical interventions before puberty.2 When indicated, TGD youth may start gonadotropin-releasing hormone analogs, which have been used in pediatrics since the 1980s. They also may go on to receive gender-affirming hormones or surgical interventions, all of which are supported by a wealth of research on their safety and effectiveness. It’s for this reason that GAC has been reified in numerous reputable professional guidelines, including the American Medical Association, the Endocrine Society, the American Academy of Pediatrics, and the American Psychiatric Association.3
Gender-Affirming Care is not Child Abuse
Child maltreatment is a serious problem, with estimates as high as 1 in 4 children experiencing some form of child abuse or neglect in their lifetime.5 The weaponization of child abuse in the discourse around GAC is fallacious and counterproductive, and it has led to numerous real threats to children’s safety and well-being.
There has been a recent deluge of legislation intended to limit access to GAC. Numerous states have introduced and passed bills that label supportive caregivers as abusive, and threaten them with child protective services investigations and child removal if they consent to GAC.6,7 Multiple bills also outline various civil and criminal penalties medical providers face if they provide GAC. These penalties include loss of medical licenses, fines up to $500 000, and criminal charges.1
Examination of the evidence and expert opinions highlight how these legislative efforts are, at minimum, the result of a lack of understanding, and in some cases fueled by malice and a desire to spread misinformation to propel forward an antitransgender agenda.8 Contrary to arguments put forth in anti-GAC legislative efforts,6–8 GAC is not a form of child physical abuse, emotional abuse, or medical child abuse.
First, we will consider child physical abuse, acts that cause physical injury to children. There are wide-ranging health impacts of physical abuse that include diabetes, cardiovascular disease, anxiety, depression. Physical abuse can result in executive functioning challenges, altered brain anatomy, and functional changes, as well as epigenetic effects.9
GAC is not child physical abuse. Unlike child physical abuse, GAC does not cause harm to children. Instead, it decreases many negative health outcomes, including rates of depression, and improves well-being for children and adolescents.7 GAC has not been shown to lead to short- or long-term negative health effects, and in fact, the benefits of GAC have been shown to far outweigh the risks.2 GAC does not, therefore, constitute physical abuse.
Opponents have argued that GAC is a form of medical child abuse (MCA).6–8 MCA refers to a child receiving unnecessary and harmful or potentially harmful medical care because of a caregiver’s overt actions including exaggeration of symptoms, lying about the history or simulating physical findings, or intentionally inducing illness in their child.10
GAC is not MCA. Although caregivers are vital supports in a child’s gender journey, the provision of gender-affirming medical and surgical care necessitates an alignment of the child’s goals with the evidence-based treatment plan determined most appropriate by the medical team. As a testament to GAC being patient driven, studies have found that the vast majority of youth who initiated medication intervention continue these treatments when followed in adulthood.11
In summary, in contrast to MCA where a child receives harmful and unnecessary medical care because of the design of the caregiver, GAC reduces the well-documented negative health repercussions of untreated GD, and is patient driven, with interventions only pursued when they serve to achieve the patient’s goals.
Denying GAC is Medical Neglect
Although there is no evidence to support the idea that providing GAC constitutes child maltreatment, there is evidence that denying such care results in significant harm to children and meets diagnostic criteria for medical neglect. Medical neglect refers to the failure to provide necessary medical care to a child, which in turn leads to or has the potential to lead to physical or psychological harm. Two of the guiding questions used in the diagnosis of medical neglect are:
is the anticipated benefit of treatment greater than its morbidity? and
is a child harmed because of a lack of medical care?
The benefits of GAC, most notably on mental health, self-esteem, and development, outweigh the risks in the majority of circumstances. GAC is, for many, lifesaving. Research highlights how transgender youth disproportionately experience negative mental health outcomes, including anxiety, depression, and suicidality.12 However, when children are supported in their gender identities and have access to GAC, they have better mental health outcomes.12,13 Some studies demonstrate that appropriate GAC, in the context of caregiver support, entirely mitigates the increased risk of depression and suicidal ideation for TGD youth.12
Children are harmed when their access to GAC is limited. It is potentially life-threatening for children to be denied GAC. Legislative restrictions mandate that caregivers and medical providers actively harm children and adolescents. Therefore, when state and federal entities limit access to GAC, their actions meet criteria for medical neglect.
Denying GAC is Emotional Abuse
Denying GAC not only represents medical neglect, but it is also state-sanctioned emotional abuse. In addition to the basic physical needs all people require for survival, humans have vital psychological needs. The degree to which these needs are met during childhood impact a child’s identity, capacities, and behaviors into adulthood.14 Emotional abuse involves actions, either as a repeated pattern or an extreme single incident, that thwart a child’s basic psychological needs.14 This form of abuse can be especially damaging because it undermines a child’s self-worth and psychological development.14 Policies that prohibit or limit a caregiver or physician’s ability to provide necessary GAC force caregivers and providers to perpetuate psychological distress.
In recent years, there has been extensive media coverage surrounding state and local bans that limit the rights of TGD individuals, including limitations on bathroom use, health care access, and participation in sports.15 Studies have shown there are direct negative health consequences for TGD individuals as a result of these bans and associated negative social media attention.4,15–17 These policies and the media coverage of them have been shown to undermine TGD children’s sense of self-worth and psychological well-being,2 and are consistent with state-sanctioned emotional abuse.
Conclusions
That children may be separated from their caregivers in certain states, on the basis of legislative efforts to classify GAC as child abuse, is abhorrent, misguided, and harmful. GAC is not child abuse, and the rhetoric asserting that GAC is equivalent to child maltreatment is fallacious. On the basis of the definitions of emotional abuse and medical neglect, as well as the numerous studies that highlight the many benefits of GAC, withholding GAC from youth represents a form of child maltreatment. There is a growing number of policies targeting TGD youth. These policies jeopardize the well-being of children, and governments or individuals who restrict children from accessing this care should be held to account. We must advocate for the fair treatment and inclusion of TGD children in our society by ensuring they receive the medical care and support they need to thrive. Figure 1 outlines specific ways to advocate.
All children deserve love, acceptance, and care. Parents should be commended, not punished, for accepting their children for who they are. Physicians should similarly be supported, not penalized both professionally and mentally, for practicing evidence-based medicine. By supporting GAC, we can foster a society that promotes healthy parent–child relationships, supports evidence-based medicine, and values the well-being of all children.
Dr Emily Georges, Dr Emily Brown and Dr Rachel Silliman Cohen conceptualized the theme of the perspectives piece. Dr Emily Georges drafted the initial manuscript and Dr Rachel Silliman Cohen and Dr Emily Brown critically revised and reviewed the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.
FUNDING: No external funding.
CONFLICT OF INTEREST DISCLOSURES: The authors have indicated they have no conflicts of interest relevant to this article to disclose.
Comments
Follow-Up to McDeavitt Comment
There is a wealth of research on the safety and effectiveness of gender-affirming hormone therapy1-3 and surgical interventions4-7 in adult populations. Additionally, the potential negative repercussions for denying pediatric patients access to GAC have been well documented8-11. While the body of literature assessing long-term outcomes in pediatric patients continues to grow, in the literature that exists, there are similar trends supporting the safety and effectiveness of this treatment in improving the mental health and quality of life of TGD youth12-15. Furthermore, the body of literature that does exist is more than adequate to support GAC clinical practices and policies (Again see Reference 2 from original article).
As a perspective piece, rather than a review of the literature, a full evaluation of the existing literature fell outside the scope of this piece. Below is additional literature that exists regarding GAC. While this is in no way a comprehensive list, it highlights the research that medical providers rely on to guide their GAC shared decision making with families.. The complexity of GAC is precisely why doctors, rather than policy makers, should be interpreting the literature and working with families and patients to determine what care and support children need.
REFERENCES
1) Aldridge Z, Patel S, Guo B, Nixon E, Pierre Bouman W, Witcomb GL, Arcelus J. Long-term effect of gender-affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study. Andrology. 2021 Nov;9(6):1808-1816. doi: 10.1111/andr.12884. Epub 2020. PMID: 32777129.
2) Baker KE, Wilson LM, Sharma R, Dukhanin V, McArthur K, Robinson KA. Hormone Therapy, Mental Health, and Quality of Life Among Transgender People: A Systematic Review. J Endocr Soc. 2021;5(4):bvab011. doi: 10.1210/jendso/bvab011. PMID: 33644622; PMCID: PMC7894249.
3) Wierckx K, Van Caenegem E, Schreiner T, Haraldsen I, Fisher AD, Toye K, Kaufman JM, T'Sjoen G. Cross-sex hormone therapy in trans persons is safe and effective at short-time follow-up: results from the European network for the investigation of gender incongruence. J Sex Med. 2014;11(8):1999-2011. doi: 10.1111/jsm.12571. Epub 2014 May 14. Erratum in: J Sex Med. 2016 Apr;13(4):732. Fisher, Alessandra [corrected to Fisher, Alessandra D]. PMID: 24828032.
4) Bertrand B, Perchenet AS, Colson TR, Drai D., & Casanova D. Female-to-male transgender chest reconstruction: A retrospective study of patient satisfaction. Annales de Chirurgie Plastique Esthétique. 2017;62(4), 303–307. https://doi.org/10.1016/j.anplas.2017.05.005.
5) Buncamper ME, van der Sluis WB, van der Pas, RSD, Özer M, Smit JM, Witte BI, Bouman MB, & Mullender MG. Surgical outcome after penile inversion vaginoplasty: A retrospective study of 475 transgender women. Plastic and Reconstructive Surgery. 2016;138(5):999–1007. https://doi.org/10.1097/ PRS.0000000000002684.
6) Javier C, Crimston CR, & Barlow FK. Surgical satisfaction and quality of life outcomes reported by transgender men and women at least one year post gender-affirming surgery: A systematic literature review. International Journal of Transgender Health. 2022;23(3): 255– 273. https://doi.org/10.1080/26895269.2022.2038334.
7) Eftekhar Ardebili M, Janani L, Khazaei Z, Moradi Y, & Baradaran HR. Quality of life in people with transsexuality after surgery: A systematic review and meta-analysis. Health and Quality of Life Outcomes. 2020;18:264. https://doi.org/10.1186/s12955-020-01510-0.
8) Green AE, Price-Feeney M, Dorison SH, & Pick CJ. Self-reported conversion efforts and suicidality among US LGBTQ youths and young adults, 2018. American Journal of Public Health. 2020;110(8): 1221–1227. https://doi.org/10.2105/ajph.2020.305701.
9) Grossman AH, D’Augelli AR, Howell TJ, & Hubbard S. Parent’ reactions to transgender youth’ gender International Journal of Transgender Health S203 nonconforming expression and identity. Journal of Gay & Lesbian Social Services. 2005; 18(1): 3–16. https://doi. org/10.1300/j041v18n01_02.
10) Klein A, & Golub SA. Family rejection as a predictor of suicide attempts and substance misuse among transgender and gender nonconforming adults. LGBT Health. 2016;3(3): 193–199. https://doi.org/10.1089/lgbt.2015.0111.
11) Turban JL, King D, Carswell JM, Keuroghlian, AS. Pubertal suppression for transgender youth and risk of suicidal ideation. Pediatrics. 2020; 145(2), e20191725.
12) Marinkovic M, Newfield RS. Chest reconstructive surgeries in transmasculine youth: Experience from one pediatric center. International Journal of Transgenderism. 2017; 18:4, 376-381, DOI: 10.1080/15532739.2017.1349706..
13) Olson-Kennedy J, Warus J, Okonta V, Belzer M, & Clark LF. Chest reconstruction and chest dysphoria in transmasculine minors and young adults: Comparisons of nonsurgical and postsurgical cohorts. JAMA Pediatrics. 2018;172(5): 431–436. https://doi.org/10.1001/ jamapediatrics.2017.5440.
14) de Vries AL, Steensma TD, Doreleijers TA, Cohen-Kettenis PT. Puberty suppression in adolescents with gender identity disorder: a prospective follow-up study. J Sex Med. 2011 Aug;8(8):2276-83. doi: 10.1111/j.1743-6109.2010.01943.x. Epub 2010 Jul 14. PMID: 20646177.
15) de Vries ALC, McGuire JK, Steensma TD, Wagenaar ECF, Doreleijers TAH, & Cohen-Kettenis PT. (2014). Young adult psychological outcome after puberty suppression and gender reassignment. Pediatrics. 2014;134(4): 696–704. https://doi.org/10.1542/peds.2013-2958.
RE: Prohibition of Gender-Affirming Care as a Form of Child Maltreatment: Reframing the Discussion
In fact, there are multiple clinical research studies looking at hormonal treatment in TGD youth in which depression outcome measures did not significantly improve over time.[10-13] In the largest such study, the depression outcome measure actually significantly worsened after initiation of hormonal treatment.[14] It is also worth noting that suicidality research in this field is decidedly mixed. For example, in a recently-published study, n=2 participants taking hormonal treatment completed suicide during the study period.[15]
It is important for the health and well-being of children and adolescents in the United States that loving and supportive parents not be unjustly criminalized. However, this perspectives paper paints a complex and controversial issue as simplistic, and depicts circumspect approaches to care (i.e., any type of management that does not involve using hormonal interventions in TGD adolescents) as “abuse.” If this is the case, should doctors and parents who favor conservative management (as is increasingly the standard of care in European countries, some of which have changed guidelines after the publication of the above-mentioned systematic reviews) be considered “abusers” due to concerns about risks and a tepid evidence base? Ultimately, it is not helpful to patients, parents, or pediatricians for evidence to be misrepresented, for opinion to be stated as fact, or for the complexities of youth GAC to be ignored in favor of portraying the issue as an uncomplicated one.
1. Hembree WC, Cohen-Kettenis PT, Gooren L, et al. Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2017;102(11):3869-3903. doi:10.1210/jc.2017-01658
2. Rafferty J. Ensuring Comprehensive Care and Support for Transgender and Gender-Diverse Children and Adolescents. Pediatrics. 2018;142(4). doi:10.1542/peds.2018-2162
3. Coleman E, Radix AE, Bouman WP, et al. Standards of care for the health of transgender and gender diverse people, version 8. Int J Transgender Health. 2022;23(Suppl 1):S1-S259. doi:10.1080/26895269.2022.2100644
4. Clayton A. Gender-Affirming Treatment of Gender Dysphoria in Youth: A Perfect Storm Environment for the Placebo Effect-The Implications for Research and Clinical Practice [published correction appears in Arch Sex Behav. 2022 Dec 13;:]. Arch Sex Behav. 2023;52(2):483-494. doi:10.1007/s10508-022-02472-8
5. National Institute for Health and Care Excellence. Evidence Review: Gonadotropin releasing hormone analogues for children and adolescents with gender dysphoria. [NICE Evidence Review]. Published 2020. https://cass.independent-review.uk/nice-evidence-reviews/
6. National Institute for Health and Care Excellence. Evidence Review: Gender-affirming hormones for children and adolescents with gender dysphoria. [NICE Evidence Review]. Published 2020. https://cass.independent-review.uk/nice-evidence-reviews/
7. Ludvigsson JF, Adolfsson J, Höistad M, et al. A systematic review of hormone treatment for children with gender dysphoria and recommendations for research. Acta Paediatr. 2023. doi:10.1111/apa.16791
8. Thompson L, Sarovic D, Wilson P, et al. A PRISMA systematic review of adolescent gender dysphoria literature: 3) treatment. PLOS Global Public Health. 2023;3(8):e0001478. doi:10.1371/journal.pgph.0001478
9. Tordoff DM, Wanta JW, Collin A, et al. Mental Health Outcomes in Transgender and Nonbinary Youths Receiving Gender-Affirming Care. JAMA Netw Open. 2022;5(2):e220978. doi:10.1001/jamanetworkopen.2022.0978
10. de Vries ALC, McGuire JK, Steensma TD, et al. Young adult psychological outcome after puberty suppression and gender reassignment. Pediatrics. 2014;134(4):696-704. doi:10.1542/peds.2013-2958
11. Cantu AL, Moyer DN, Connelly KJ, Holley AL. Changes in Anxiety and Depression from Intake to First Follow-Up Among Transgender Youth in a Pediatric Endocrinology Clinic. Transgender Health. 2020;5(3):196-200. doi:10.1089/trgh.2019.0077
12. Carmichael P, Butler G, Masic U, et al. Short-term outcomes of pubertal suppression in a selected cohort of 12 to 15 year old young people with persistent gender dysphoria in the UK. PLoS One. 2021;16(2):e0243894.
13. Becker-Hebly I, Fahrenkrug S, Campion F, et al. Psychosocial health in adolescents and young adults with gender dysphoria before and after gender-affirming medical interventions: a descriptive study from the Hamburg Gender Identity Service. Eur Child Adolesc Psychiatry. 2021;30(11):1755-1767. doi:10.1007/s00787-020-01640-2
14. Hisle-Gorman E, Schvey NA, Adirim TA, et al. Mental healthcare utilization of transgender youth before and after affirming treatment. J Sex Med. 2021;18(8):1444-1454. doi:10.1016/j.jsxm.2021.05.014
15. Chen D, Berona J, Chan Y-M, et al. Psychosocial Functioning in Transgender Youth after 2 Years of Hormones. N Engl J Med. 2023;388(3):240-250. doi:10.1056/NEJMoa2206297