Passage of the first stool and urine in full-term neonates within the first 24 hours of life usually is a sign of well-being. After birth, 60% of healthy full-term neonates "stool" for the first time by 8 hours of life, 91% by 16 hours, 98.5% by 24 hours, and virtually all by 48 hours. Delay in the passage of the first stool in term neonates may be associated with lower intestinal obstruction, that is, meconium plug syndrome, Hirschsprung disease, and imperforate anus. More generalized problems such as sepsis or hypothyroidism should be considered and the maternal history should be reviewed carefully for an unanticipated complication of magnesium sulfate administration or narcotic use.

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