A male infant is born at 39 weeks’ gestation to a 25-year-old G1P1 African American woman. The pregnancy was uncomplicated and the mother received appropriate prenatal care. Results for maternal group B Streptococcus colonization and standard viral serology testing were negative. Delivery is via cesarean delivery because of breech presentation at onset of labor. At delivery, initial examination reveals a prominent tuft of white hair at the forehead hairline (Fig 1), as well as large hypopigmented macules with well-defined borders covering significant areas on the torso and the mid upper and lower extremities (Fig 2). The remainder of the physical examination is normal. Apgar scores are 9 and 9 at 1 and 5 minutes, respectively, and vital signs are normal for age. Weight, length, and head circumference are between the 25th and 50th percentiles. On the second day of life, the baby fails his click auditory...

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