A 7-year-old boy with no significant abnormal medical history presents to the emergency department of a tertiary care children’s hospital with subacute progressive increase in unusual behaviors. For the past several weeks, his parents have noted instances during conversations when he pauses for a few seconds after being spoken to before asking, “What?” Usually after the words are repeated to him, he responds appropriately, although he has also sometimes had strange responses to questions; once when asked, “Can you get that shoe?” he appeared confused then replied, “There are no cows in the house.” The instances occurred only a few times daily at first but have progressively increased in frequency to multiple times per conversation. When they have been pointed out to him, he becomes defensive and blames them on his parents not speaking loudly enough or the room being too loud. Otherwise, he has behaved and interacted normally. His...
Unusual Behaviors in a 7-year-old Boy
Dr Eichler has sponsorships of clinical trials from bluebird bio and Minoryx Therapeutics and a sponsored research agreement with Applied Genetic Technologies Corporation. Dr Eichler has spoken at an educational session sponsored by bluebird bio, has performed consulting for Ionis Pharmaceuticals, Sanofi Genzyme, and SwanBio Therapeutics, and holds equity in SwanBio Therapeutics. Drs Chang, Shao, and Srivastava have disclosed no financial relationships relevant to this article. This commentary does not contain a discussion of an unapproved/investigative use of a commercial product/device.
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Lawrence Chang, Diane D. Shao, Florian S. Eichler, Siddharth Srivastava; Unusual Behaviors in a 7-year-old Boy. Pediatr Rev January 2021; 42 (Supplement_1): S122–S125. https://doi.org/10.1542/pir.2019-0244
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