A healthy, immunized 8-year-old girl presents to the pediatric emergency department (PED) with 10 days of fever, 4 days of abdominal pain, 3 days of nonbloody diarrhea (3–4 episodes daily), 2 episodes of nonbloody and nonbilious emesis, and a new transient urticarial rash. She returned from India 5 weeks before presentation and developed sore throat and fever 4 weeks before presentation. At that time, she was diagnosed as having streptococcal pharyngitis and was prescribed amoxicillin. After 3 days of taking amoxicillin, she became afebrile, she then completed the 10-day course and remained afebrile for another 5 days off amoxicillin. However, 10 days before presentation, she became febrile again. She tested positive for streptococcal pharyngitis again 2 days later and was prescribed cefdinir for presumed treatment failure. She continued to have fever, and the day before presentation, 8 days on cefdinir, she developed an urticarial rash, with conjunctival injection. Given concerns...

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