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Human metapneumovirus (hMPV) causes acute respiratory tract illness in people of all ages and is one of the leading causes of bronchiolitis in infants. In children, hMPV also causes pneumonia, asthma exacerbations, croup, upper respiratory tract infections (URIs), and acute otitis media; these may be accompanied by fever. As with other respiratory viral infections, secondary bacterial pneumonia can occur. hMPV is associated with acute exacerbations of chronic obstructive pulmonary disease (COPD) and pneumonia in adults. Otherwise healthy, young children infected with hMPV usually have mild or moderate respiratory symptoms, but some young children have severe disease requiring hospitalization. hMPV...

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