Salmonella Infections

Nontyphoidal Salmonella (NTS) infection is associated with a spectrum of illness ranging from asymptomatic gastrointestinal tract carriage to gastroenteritis, urinary tract infection, bacteremia, and focal infections, including meningitis, brain abscess, and osteomyelitis (to which people with sickle cell anemia are predisposed). The most common illness associated with NTS infection is gastroenteritis, with manifestations of diarrhea, abdominal cramps, and fever. The site of infection usually is the distal small intestine as well as the colon. Sustained or intermittent bacteremia can occur, and focal infections are recognized in up to 10% of patients with NTS bacteremia. In the United States, the...