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The role of Ureaplasma species in human disease is controversial. There has been an inconsistent association between presence of Ureaplasma urealyticum and nongonococcal urethritis (NGU). Without treatment, the urethritis usually resolves within 1 to 6 months. There also has been an inconsistent relationship of infection by Ureaplasma species with prostatitis and epididymitis in male individuals and upper genital tract syndromes in female individuals, including salpingitis, endometritis, and pelvic inflammatory disease.329 Ureaplasma organisms commonly are detected in placentas with histologic chorioamnionitis (now known as intra-amniotic infection), and studies suggest that there is an association of upper genital tract infection by...

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