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Diagnosis Detective Archive

October 2, 2024

Diagnosis Detective: Can you solve it?

Red Book Online Presents: Diagnosis Detective | Archive

Red Book Online's Diagnosis Detective challenges you to diagnose the case based on the clinical information presented. 

Interested in submitting a case? Read the Author Instructions.

Case 1: October 2023

The patient is a 3-year-old fully vaccinated male with a past medical history of Alport Syndrome status post renal transplant and is currently receiving 600 mg/m2/dose of mycophenolate mofetil twice daily...

Case 2: November 2023

A 6-week-old female infant is evaluated in the emergency department for a one-day history of decreased oral intake...

Case 3: December 2023

A 15-year-old previously healthy male presents with 10 days of right (R) inguinal lymphadenopathy. He also endorses dysuria, but denied fever, rash, URI symptoms or change in mental status...

Case 4: January 2024

An 8-year-old presents with acute onset of fever to 102°F, sore throat, and headache. The child has a slight runny nose but their mother reports the child “always has a runny nose”...

Case 5: February 2024

A 14-year-old previously healthy female presents with 11 days of right (R) elbow pain that worsened one night prior to presentation. The pain is worse with movement and radiates up the arm...

Case 6: March 2024

An 18-month-old girl presents to a pediatric emergency department with a 3-day history of fever, sore throat, and bilateral cervical lymph node swelling...

Case 7: April 2024

A female infant was born at 36 weeks and 6 days gestation to a 37-year-old mother G3P0020 with a history of polycystic ovarian syndrome...

Case 8: May 2024

A previously healthy, fully-vaccinated 11-month-old female presents to the emergency department with redness behind her right ear that was first noted earlier that morning...

Case 9: June 2024

A 14-year-old previously healthy female presents with four days of fever, diarrhea, headache, and rash. She returned from a month-long trip to the Dominican Republic one week ago...

Case 10: July 2024

A 2-year-old previously healthy male presents with a 5-week history of left-sided neck swelling. The swelling began as a painless, 3-centimeter lump on the left side of the neck...

Case 11: August 2024

A 16-year-old previously healthy male presents with 2 months of intermittent fever, cough, myalgia, and a rash on the lower extremities...

Case 12: September 2024

A 14-year-old previously healthy female presents with 7 days of left-sided facial and neck swelling and tender cervical lymphadenopathy...


Launched in October 2023, Diagnosis Detective on Red Book Online challenges you to solve a new infectious disease case every month. Developed by a dedicated subteam of the American Academy of Pediatrics Committee on Infectious Diseases, this feature offers:

Monthly Diagnostic Challenge: Return monthly to test your diagnostic skills with new infectious disease content.

Interactive Quiz: Actively participate and learn by solving real-world infectious disease cases.

Teaching/Learning: Use the valuable infectious disease educational content to learn, as well as reference as needed.

Social Sharing: Share your success on social media platforms—Facebook, LinkedIn, and Twitter/X.

Archived Cases: Challenge yourself with previous cases, which will be archived, for continued learning, or if you missed a previous month’s case.

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