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TABLE 3

Admission and Hospital Course Laboratory Valuesa of Patients Hospitalized for COVID-19, by Age Group, 5 Hospitals,b United States, July to August 2021, N = 759

<1 Years
(n = 176)
1–4 Years
(n = 122)
5–11 Years
(n = 143)
12–17 Years
(n = 272)
18–20 Years
(n = 46)
WBC, 109/L      
 Admission, n 54 54 73 145 31 
  Median (IQR) 9.8 (6.3–13.0) 8.1 (5.5–13.9) 5.8 (4.3–8.5) 5.3 (3.9–7.5) 5.6 (4.5–8.1) 
 Peak, n 62 54 72 147 33 
  Median (IQR) 10.7 (6.6–13.4) 9.8 (6.0–13.9) 6.8 (4.9–9.8) 7.1 (4.8–10.5) 7.2 (4.8–11.3) 
 Nadir, n 62 54 73 147 33 
  Median (IQR) 8.1 (5.7–12.1) 6.9 (4.7–12.0) 4.9 (3.5–7.4) 4.8 (3.6–6.8) 4.6 (4.3–7.0) 
Hemoglobin, g/dL      
 Admission, n 36 31 39 96 27 
  Median (IQR) 11.0 (9.8–12.8) 11.4 (9.7–12.5) 12.4 (11.3–13.6) 13.2 (11.8–14.8) 13.3 (12.2–15.0) 
 Nadir, n 29 24 35 91 27 
  Median (IQR) 10.8 (8.8–11.9) 10.8 (9.4–12.3) 12.3 (10.9–13.9) 12.6 (10.3–14.1) 12.2 (10.9–13.8) 
Platelets, cells/mm3      
 Admission, n 65 54 74 149 32 
  Median (IQR) 362 (263–451) 273 (183–355) 231 (146–306) 211 (157–275) 189 (161–260) 
 Peak, n 64 53 73 151 34 
  Median (IQR) 370 (280–470) 296 (234–367) 270 (191–359) 264 (197–350) 258 (191–331) 
 Nadir, n 63 53 74 151 34 
  Median (IQR) 333 (249–412) 239 (149–314) 208 (144–270) 195 (143–242) 177 (132–227) 
D-dimer, mg FEU/L      
 Admission, n 12 19 49 166 18 
  Median (IQR) 0.9 (0.7–1.3) 0.7 (0.5–1.3) 0.9 (0.5–1.7) 1.0 (0.6–1.6) 0.9 (0.6–1.6) 
 Peak, n 13 22 58 173 23 
  Median (IQR) 0.9 (0.9–1.1) 0.7 (0.5–1.5) 1.0 (0.5–2.0) 1.0 (0.6–1.9) 1.0 (0.6–2.8) 
Creatinine, mg/dL      
 Admission, n 73 68 99 209 32 
  Median (IQR) 0.3 (0.2–0.3) 0.3 (0.2–0.4) 0.5 (0.3–0.5) 0.7 (0.5–0.8) 0.7 (0.5–0.9) 
 Peak, n 75 67 99 213 36 
  Median (IQR) 0.3 (0.2–0.3) 0.3 (0.2–0.4) 0.5 (0.4–0.6) 0.7 (0.6–0.9) 0.8 (0.5–1.0) 
AST, U/L      
 Peak, n 66 51 90 187 34 
  Median (IQR) 47 (31–70) 57 (41–89) 62 (34–92) 59 (35–107) 77 (43–121) 
ALT, U/L      
 Peak, n 66 51 90 187 34 
  Median (IQR) 23 (17–34) 27 (17–40) 31 (16–71) 40 (22–100) 57 (29–141) 
CRP, mg/L      
 Admission, n 40 39 69 162 23 
  Median (IQR) 11.0 (5.0–41.0) 26.0 (6.0–88.0) 15.0 (7.0–45.0) 36.5 (14.0–72.0) 54.0 (24.0–70.0) 
 Peak, n 43 39 74 172 28 
  Median (IQR) 14.0 (5.0–45.0) 30.0 (8.0–88.0) 20.5 (9.0–56.0) 42.5 (14.0–82.5) 61.0 (39.5–102) 
Procalcitonin, ng/mL      
 Admission, n 48 33 55 131 17 
  Median (IQR) 0.2 (0.1–0.4) 1.1 (0.2–7.1) 0.1 (0.1–0.4) 0.2 (0.1–0.4) 0.1 (0.1–0.2) 
 Peak, n 49 32 62 141 19 
  Median (IQR) 0.2 (0.1–0.3) 1.1 (0.2–6.5) 0.1 (0.1–0.4) 0.2 (0.1–0.4) 0.1 (0.1–0.2) 
Ferritin, ng/mL      
 Admission, n 13 22 45 122 13 
  Median (IQR) 140 (75–253) 94 (62–201) 156 (92–300) 243 (126–447) 305 (205–580) 
 Peak, n 16 25 52 132 17 
  Median (IQR) 175 (83–486) 99 (67–207) 192 (101, 377) 243 (128–559) 305 (109–629) 
<1 Years
(n = 176)
1–4 Years
(n = 122)
5–11 Years
(n = 143)
12–17 Years
(n = 272)
18–20 Years
(n = 46)
WBC, 109/L      
 Admission, n 54 54 73 145 31 
  Median (IQR) 9.8 (6.3–13.0) 8.1 (5.5–13.9) 5.8 (4.3–8.5) 5.3 (3.9–7.5) 5.6 (4.5–8.1) 
 Peak, n 62 54 72 147 33 
  Median (IQR) 10.7 (6.6–13.4) 9.8 (6.0–13.9) 6.8 (4.9–9.8) 7.1 (4.8–10.5) 7.2 (4.8–11.3) 
 Nadir, n 62 54 73 147 33 
  Median (IQR) 8.1 (5.7–12.1) 6.9 (4.7–12.0) 4.9 (3.5–7.4) 4.8 (3.6–6.8) 4.6 (4.3–7.0) 
Hemoglobin, g/dL      
 Admission, n 36 31 39 96 27 
  Median (IQR) 11.0 (9.8–12.8) 11.4 (9.7–12.5) 12.4 (11.3–13.6) 13.2 (11.8–14.8) 13.3 (12.2–15.0) 
 Nadir, n 29 24 35 91 27 
  Median (IQR) 10.8 (8.8–11.9) 10.8 (9.4–12.3) 12.3 (10.9–13.9) 12.6 (10.3–14.1) 12.2 (10.9–13.8) 
Platelets, cells/mm3      
 Admission, n 65 54 74 149 32 
  Median (IQR) 362 (263–451) 273 (183–355) 231 (146–306) 211 (157–275) 189 (161–260) 
 Peak, n 64 53 73 151 34 
  Median (IQR) 370 (280–470) 296 (234–367) 270 (191–359) 264 (197–350) 258 (191–331) 
 Nadir, n 63 53 74 151 34 
  Median (IQR) 333 (249–412) 239 (149–314) 208 (144–270) 195 (143–242) 177 (132–227) 
D-dimer, mg FEU/L      
 Admission, n 12 19 49 166 18 
  Median (IQR) 0.9 (0.7–1.3) 0.7 (0.5–1.3) 0.9 (0.5–1.7) 1.0 (0.6–1.6) 0.9 (0.6–1.6) 
 Peak, n 13 22 58 173 23 
  Median (IQR) 0.9 (0.9–1.1) 0.7 (0.5–1.5) 1.0 (0.5–2.0) 1.0 (0.6–1.9) 1.0 (0.6–2.8) 
Creatinine, mg/dL      
 Admission, n 73 68 99 209 32 
  Median (IQR) 0.3 (0.2–0.3) 0.3 (0.2–0.4) 0.5 (0.3–0.5) 0.7 (0.5–0.8) 0.7 (0.5–0.9) 
 Peak, n 75 67 99 213 36 
  Median (IQR) 0.3 (0.2–0.3) 0.3 (0.2–0.4) 0.5 (0.4–0.6) 0.7 (0.6–0.9) 0.8 (0.5–1.0) 
AST, U/L      
 Peak, n 66 51 90 187 34 
  Median (IQR) 47 (31–70) 57 (41–89) 62 (34–92) 59 (35–107) 77 (43–121) 
ALT, U/L      
 Peak, n 66 51 90 187 34 
  Median (IQR) 23 (17–34) 27 (17–40) 31 (16–71) 40 (22–100) 57 (29–141) 
CRP, mg/L      
 Admission, n 40 39 69 162 23 
  Median (IQR) 11.0 (5.0–41.0) 26.0 (6.0–88.0) 15.0 (7.0–45.0) 36.5 (14.0–72.0) 54.0 (24.0–70.0) 
 Peak, n 43 39 74 172 28 
  Median (IQR) 14.0 (5.0–45.0) 30.0 (8.0–88.0) 20.5 (9.0–56.0) 42.5 (14.0–82.5) 61.0 (39.5–102) 
Procalcitonin, ng/mL      
 Admission, n 48 33 55 131 17 
  Median (IQR) 0.2 (0.1–0.4) 1.1 (0.2–7.1) 0.1 (0.1–0.4) 0.2 (0.1–0.4) 0.1 (0.1–0.2) 
 Peak, n 49 32 62 141 19 
  Median (IQR) 0.2 (0.1–0.3) 1.1 (0.2–6.5) 0.1 (0.1–0.4) 0.2 (0.1–0.4) 0.1 (0.1–0.2) 
Ferritin, ng/mL      
 Admission, n 13 22 45 122 13 
  Median (IQR) 140 (75–253) 94 (62–201) 156 (92–300) 243 (126–447) 305 (205–580) 
 Peak, n 16 25 52 132 17 
  Median (IQR) 175 (83–486) 99 (67–207) 192 (101, 377) 243 (128–559) 305 (109–629) 

ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, C-reactive protein; WBC, white blood cells.

a Normal age- and sex-specific values were referenced from the Harriet Lane Handbook.25  Laboratory measurements > or < than a value of detection were designated as equal to those values.

b Laboratory data were not available from Children’s National Hospital, Washington, DC.

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