High-Risk Groups for Influenza Complications
| Category . | Description . |
|---|---|
| Demographic characteristics | Children <5 y, especially those <2 ya |
| Residents of a chronic care facility or nursing home | |
| Underlying condition or treatment with common examplesb | |
| Chronic pulmonary disease | Asthma |
| Cystic fibrosis | |
| Compromised respiratory function (eg, requiring mechanical ventilation, tracheostomy) | |
| Cardiovascular disease | Hemodynamically significant conditions (excluding hypertension alone) |
| Kidney disease | Chronic kidney disease, including end-stage kidney disease |
| Dialysis | |
| Hepatic disease | Chronic liver disease |
| Cirrhosis11,12 | |
| Hematologic disease | Sickle cell disease |
| Other hemoglobinopathies | |
| Metabolic disorders | Diabetes mellitus |
| Neurologic and neurodevelopmental conditions | Cerebral palsy |
| Epilepsy | |
| Stroke | |
| Intellectual developmental disorder | |
| Moderate to severe developmental delay | |
| Muscular dystrophy | |
| Spinal cord injury | |
| Extreme obesity | BMI ≥40 for adultsc |
| Immunosuppression | Receipt of immuncompromising medications |
| Congenital or acquired immune deficiency, including HIV | |
| Asplenia | |
| Receiving treatment with aspirin or salicylate-containing therapiesd | |
| Pregnancy and up to 2 wk’ postpartum | |
| Category . | Description . |
|---|---|
| Demographic characteristics | Children <5 y, especially those <2 ya |
| Residents of a chronic care facility or nursing home | |
| Underlying condition or treatment with common examplesb | |
| Chronic pulmonary disease | Asthma |
| Cystic fibrosis | |
| Compromised respiratory function (eg, requiring mechanical ventilation, tracheostomy) | |
| Cardiovascular disease | Hemodynamically significant conditions (excluding hypertension alone) |
| Kidney disease | Chronic kidney disease, including end-stage kidney disease |
| Dialysis | |
| Hepatic disease | Chronic liver disease |
| Cirrhosis11,12 | |
| Hematologic disease | Sickle cell disease |
| Other hemoglobinopathies | |
| Metabolic disorders | Diabetes mellitus |
| Neurologic and neurodevelopmental conditions | Cerebral palsy |
| Epilepsy | |
| Stroke | |
| Intellectual developmental disorder | |
| Moderate to severe developmental delay | |
| Muscular dystrophy | |
| Spinal cord injury | |
| Extreme obesity | BMI ≥40 for adultsc |
| Immunosuppression | Receipt of immuncompromising medications |
| Congenital or acquired immune deficiency, including HIV | |
| Asplenia | |
| Receiving treatment with aspirin or salicylate-containing therapiesd | |
| Pregnancy and up to 2 wk’ postpartum | |
Source: Adapted from Centers for Disease Control and Prevention. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, United States, 2022–2023 influenza season. MMWR Recomm Rep. 2022; in press.
Regardless of the presence of underlying medical conditions.
List of examples is not exhaustive.
Not well defined in children but could consider BMI ≥99% for age.
Applies to children and adolescents aged <19 years who may be at increased risk of Reye syndrome.