TABLE 16

Prevalence of Abnormal HOMA-IR (n = 10)

First AuthorCountryAges (y)NDefinition of AbnormalSubgroup (eg, M/F)TotalHealthyOverweightClass IClass IIClass IIIPNotesWeight definitionsPopulation Info
Bindler USA 11–14 151 >2.7 No  22.7  62.5   <.001    
Valerio Italy 3–16 150 >2.5 children; >4.0 adolescents Children   40.8   <.001    
     Adolescents   41.2   <.002    
Turchiano USA 14–18 1185 >3.99   4.5 12.4 37.8   <.001   Youth of urban minoritized groups 
Perez US (Puerto Rico) 12–18 101 ≥3.16   35.6 81.3    <.001    
Peplies Europe 3–10.9 3348 >95th  17.8 10.9 36.5 66.7       
Michalsky USA 13–19 242 ≥4.0  71.1   71.2 71.2 70.8 >.99  1: 30 < 50 BMI, 2: 50 < 60; 3: >60 Bariatric surgery patients 
Caserta Italy 11–13 646 >2.28 males, >2.67 females Males  13.1 26.7 54.7   <.05    
     Females  11.8 37.1 65.5   <.05    
Serap Turkey 6–16 284 >2.5 Males  3.8  47.2   <.001   Pediatric endocrinology patients 
     Females  8.6  56.7   <.001    
Manios Greece 10–12 522 >2.10 (97.5th %ile of NW) No 9.2 2.9 10.5 31.0   <.001    
Gunes USA 11–18 363 3.16 Males   60 68   .402   Adolescent clinic patients 
     Females   48.2 44.7   <.001   Adolescent clinic patients 
First AuthorCountryAges (y)NDefinition of AbnormalSubgroup (eg, M/F)TotalHealthyOverweightClass IClass IIClass IIIPNotesWeight definitionsPopulation Info
Bindler USA 11–14 151 >2.7 No  22.7  62.5   <.001    
Valerio Italy 3–16 150 >2.5 children; >4.0 adolescents Children   40.8   <.001    
     Adolescents   41.2   <.002    
Turchiano USA 14–18 1185 >3.99   4.5 12.4 37.8   <.001   Youth of urban minoritized groups 
Perez US (Puerto Rico) 12–18 101 ≥3.16   35.6 81.3    <.001    
Peplies Europe 3–10.9 3348 >95th  17.8 10.9 36.5 66.7       
Michalsky USA 13–19 242 ≥4.0  71.1   71.2 71.2 70.8 >.99  1: 30 < 50 BMI, 2: 50 < 60; 3: >60 Bariatric surgery patients 
Caserta Italy 11–13 646 >2.28 males, >2.67 females Males  13.1 26.7 54.7   <.05    
     Females  11.8 37.1 65.5   <.05    
Serap Turkey 6–16 284 >2.5 Males  3.8  47.2   <.001   Pediatric endocrinology patients 
     Females  8.6  56.7   <.001    
Manios Greece 10–12 522 >2.10 (97.5th %ile of NW) No 9.2 2.9 10.5 31.0   <.001    
Gunes USA 11–18 363 3.16 Males   60 68   .402   Adolescent clinic patients 
     Females   48.2 44.7   <.001   Adolescent clinic patients 

NW, normal weight.

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