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APPENDIX 4

EEG in Pediatric Brain Death: Diagnostic Yield From First Versus Any Study

StudyTotal # Pts in Study% Patients With ECS on EEG#1% Patients With ECS on Any EEG% Pts With ECS on f/u EEG When First EEG Had ECS% Pt With ECS on Later EEGs When First EEG Had Activity
Ruiz-Garcia et al, 2000 (60) 125 72% (88/122) 91% (111/122) NA 68% (23/34) 
Drake et al, 198655  61 70% (33/47) 91% (43/47) 100% (17/17) 71% (10/14) 
Parker et al, 199536  60 100% (9/9) 100% (9/9) NA NA 
Alvarez et al, 198856  52 100% (52/52) 100% (52/52) 100% (28/28) NA 
Ashwal, 199354  52 85% (28/33) 85% (28/33) 100% (3/3) 0% (0/1) 
Ruiz-Lopez et al, 199961  51 48% (14/29) 72% (21/29) NA 47% (7/15) 
Ashwal & Schneider, 198965  18 50% (9/18) 78% (14/18) 88% (7/8) 56% (5/9) 
Holzman et al, 198362  18 61% (11/18) 67% (12/18) 67% (2/3) 14% (1/7) 
Ashwal et al, 197758  15 67% (10/15) 73% (11/15) 100% (2/2) 20% (1/5) 
Coker et al, 198659  14 100% (11/11) 100% (11/11) 100% (5/5) NA 
Furgiuele et al, 198463  11 100% (10/10) 100% (10/10) NA NA 
Okuyaz et al, 200464  100% (8/8) 100% (8/8) NA NA 
Total 485 76% (283/372) 89% (330/372) 97% (64/66) 55% (47/85) 
StudyTotal # Pts in Study% Patients With ECS on EEG#1% Patients With ECS on Any EEG% Pts With ECS on f/u EEG When First EEG Had ECS% Pt With ECS on Later EEGs When First EEG Had Activity
Ruiz-Garcia et al, 2000 (60) 125 72% (88/122) 91% (111/122) NA 68% (23/34) 
Drake et al, 198655  61 70% (33/47) 91% (43/47) 100% (17/17) 71% (10/14) 
Parker et al, 199536  60 100% (9/9) 100% (9/9) NA NA 
Alvarez et al, 198856  52 100% (52/52) 100% (52/52) 100% (28/28) NA 
Ashwal, 199354  52 85% (28/33) 85% (28/33) 100% (3/3) 0% (0/1) 
Ruiz-Lopez et al, 199961  51 48% (14/29) 72% (21/29) NA 47% (7/15) 
Ashwal & Schneider, 198965  18 50% (9/18) 78% (14/18) 88% (7/8) 56% (5/9) 
Holzman et al, 198362  18 61% (11/18) 67% (12/18) 67% (2/3) 14% (1/7) 
Ashwal et al, 197758  15 67% (10/15) 73% (11/15) 100% (2/2) 20% (1/5) 
Coker et al, 198659  14 100% (11/11) 100% (11/11) 100% (5/5) NA 
Furgiuele et al, 198463  11 100% (10/10) 100% (10/10) NA NA 
Okuyaz et al, 200464  100% (8/8) 100% (8/8) NA NA 
Total 485 76% (283/372) 89% (330/372) 97% (64/66) 55% (47/85) 

EEG Electroencephalogram.

ECS Electrocerebral silence.

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