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APPENDIX 5

CBF in Pediatric Brain Death: Diagnostic Yield From First Versus Any Study

StudyTotal # of Pts in StudyCBF#1: % Patients With Absent CBF*% Patients With Absent CBF on Any Study**% Pts With No CBF on f/u Study When First Study Had Shown No CBF% Pt With No CBF on Later Study When First Study Had CBF Present
Shimizu et al, 200066  228 100% (27/27) 100% (27/27) NA NA 
Ruiz-Garcia et al, 200060  125 92% (83/90) 92% (83/90) NA NA 
Drake et al, 198655  61 68% (32/47) 81% (38/47) 100% (17/17) 40% (6/15) 
Parker et al, 199536  60 87% (26/30) 87% (26/30) NA NA 
Coker et al, 198659  55 100% (55/55) 100% (55/55) NA NA 
Ashwal, 199354  52 86% (19/22) 86% (19/22) NA NA 
Ahmann et al, 198767  32 83% (6/6) 83% (6/6) NA NA 
Ashwal &Schneider, 198965  18 65% (11/17) 65% (11/17) 71% (5/7) 0% (0/3) 
Holzman et al, 198362  18 39% (7/18) 44% (8/18) 100% (2/2) 9% (1/11) 
Ashwal et al, 197758  15 100% (11/11) 100% (11/11) NA NA 
Schwartz et al, 198468  100% (9/9) 100% (9/9) NA NA 
Okuyaz et al, 200464  75% (6/8) 100% (8/8) NA 100% (2/2) 
Total 681 86% (292/340) 89% (301/340) 92% (24/26) 26% (9/34) 
StudyTotal # of Pts in StudyCBF#1: % Patients With Absent CBF*% Patients With Absent CBF on Any Study**% Pts With No CBF on f/u Study When First Study Had Shown No CBF% Pt With No CBF on Later Study When First Study Had CBF Present
Shimizu et al, 200066  228 100% (27/27) 100% (27/27) NA NA 
Ruiz-Garcia et al, 200060  125 92% (83/90) 92% (83/90) NA NA 
Drake et al, 198655  61 68% (32/47) 81% (38/47) 100% (17/17) 40% (6/15) 
Parker et al, 199536  60 87% (26/30) 87% (26/30) NA NA 
Coker et al, 198659  55 100% (55/55) 100% (55/55) NA NA 
Ashwal, 199354  52 86% (19/22) 86% (19/22) NA NA 
Ahmann et al, 198767  32 83% (6/6) 83% (6/6) NA NA 
Ashwal &Schneider, 198965  18 65% (11/17) 65% (11/17) 71% (5/7) 0% (0/3) 
Holzman et al, 198362  18 39% (7/18) 44% (8/18) 100% (2/2) 9% (1/11) 
Ashwal et al, 197758  15 100% (11/11) 100% (11/11) NA NA 
Schwartz et al, 198468  100% (9/9) 100% (9/9) NA NA 
Okuyaz et al, 200464  75% (6/8) 100% (8/8) NA 100% (2/2) 
Total 681 86% (292/340) 89% (301/340) 92% (24/26) 26% (9/34) 
*

# pts with no CBF on first study/# pts with first CBF study.

**

# pts with no CBF on any study/# pts with any CBF.

CBF Cerebral blood flow.

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