American Academy of Pediatrics

TABLE 1

Nutrients That Particularly Affect Early Brain Development and Demonstrate a Critical or Sensitive Period

Macronutrients
Protein^a
Specific fats (eg, LC-PUFAs)^a
Glucose
Micronutrients
Zinc^a
Copper^a
Iodine^a
Iron^a
Selenium
Vitamins and cofactors
B vitamins (B₆, B₁₂)
Vitamin A
Vitamin K
Folate^a
Choline^a

Macronutrients
Protein^a
Specific fats (eg, LC-PUFAs)^a
Glucose
Micronutrients
Zinc^a
Copper^a
Iodine^a
Iron^a
Selenium
Vitamins and cofactors
B vitamins (B₆, B₁₂)
Vitamin A
Vitamin K
Folate^a
Choline^a

LC-PUFA, long-chain polyunsaturated fatty acid. Reprinted with permission from Georgieff MK, Brunette KE, Tran PV. Early life nutrition and neural plasticity. Dev Psychopathol. 2015;27(2):415.

Nutrients that meet the principles for demonstrating a critical or sensitive period during development.

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