American Academy of Pediatrics

TABLE 1

Response Rates in RCTs of Antidepressants Based on Clinical Global Impression

Medication	Drug, %	Placebo, %	P
Fluoxetine⁴⁵^,^a	56	33	.02
Fluoxetine⁴⁶	52	37	.03
Fluoxetine⁴⁷	61	35	.001
Paroxetine⁴⁸^,^b	66	48	.02
Paroxetine⁴⁹	69	57	NS
Paroxetine⁴⁹	65	46	.005
Citalopram⁵⁰	47	45	NS
Citalopram⁵¹	51	53	NS
Sertraline⁵²	63	53	.05
Escitalopram⁵³	63	52	.14
Escitalopram⁵⁴	64	53	.03

Medication	Drug, %	Placebo, %	P
Fluoxetine⁴⁵^,^a	56	33	.02
Fluoxetine⁴⁶	52	37	.03
Fluoxetine⁴⁷	61	35	.001
Paroxetine⁴⁸^,^b	66	48	.02
Paroxetine⁴⁹	69	57	NS
Paroxetine⁴⁹	65	46	.005
Citalopram⁵⁰	47	45	NS
Citalopram⁵¹	51	53	NS
Sertraline⁵²	63	53	.05
Escitalopram⁵³	63	52	.14
Escitalopram⁵⁴	64	53	.03

NS, not significant.

Fluoxetine alone compared with placebo.

Paroxetine compared with placebo.