TABLE 4

Evaluation and Administration of Immunization Status of Adopted Children

• Infectious diseases (for updates on infectious disease screening, please consult the AAP Red Book17
 ○ Hepatitis B 
  • Test for HBsAb; if negative, give age-appropriate immunization 
 ○ Diphtheria, pertussis, and tetanus toxoids 
  • Immunize as appropriate for age. Serologic testing for antitoxoid antibodies 4 wk after dose 1 if severe local reaction. 
  • If previously received ≥3 doses, serologic testing for antitoxoid antibody to diphtheria and tetanus toxins before administrating additional doses or administer a single dose of diphtheria and tetanus-containing vaccine, followed by serologic testing 1 mo later for antitoxoid antibody. 
 ○ Haemophilus influenza type b (Hib) 
  • Age-appropriate immunization 
  • If >12 mo of age, serologic testing for Hib immunoglobulin G (IgG) is available 
 ○ Pertussis 
  • There is no serologic test routinely available, but may use antibodies to diphtheria or tetanus as a marker that vaccine was previously given. 
 ○ Poliovirus 
  • Immunize with inactivated poliovirus vaccine (IPV) per routine schedule 
  • An alternative to vaccination would be to perform serologic testing for neutralizing antibody to poliovirus types 1, 2, and 3 or give a single dose of IPV, followed by serologic testing. 
 ○ Measles-Mumps-Rubella (MMR) 
  • Immunize with MMR or obtain measles antibody concentration. If positive, give MMR vaccine to protect against mumps and rubella. 
  • An alternative would be to perform serologic testing for IgG antibody to vaccine viruses, indicated by the immunization record. 
 ○ Varicella 
  • Give age-appropriate immunization if there is not a reliable history of previous disease or serologic evidence of disease by varicella antibody. 
 ○ Pneumococcal 
  • Give age-appropriate immunization. 
  • If >12 mo of age, serologic testing for IgG for serotypes 7-14 
• Infectious diseases (for updates on infectious disease screening, please consult the AAP Red Book17
 ○ Hepatitis B 
  • Test for HBsAb; if negative, give age-appropriate immunization 
 ○ Diphtheria, pertussis, and tetanus toxoids 
  • Immunize as appropriate for age. Serologic testing for antitoxoid antibodies 4 wk after dose 1 if severe local reaction. 
  • If previously received ≥3 doses, serologic testing for antitoxoid antibody to diphtheria and tetanus toxins before administrating additional doses or administer a single dose of diphtheria and tetanus-containing vaccine, followed by serologic testing 1 mo later for antitoxoid antibody. 
 ○ Haemophilus influenza type b (Hib) 
  • Age-appropriate immunization 
  • If >12 mo of age, serologic testing for Hib immunoglobulin G (IgG) is available 
 ○ Pertussis 
  • There is no serologic test routinely available, but may use antibodies to diphtheria or tetanus as a marker that vaccine was previously given. 
 ○ Poliovirus 
  • Immunize with inactivated poliovirus vaccine (IPV) per routine schedule 
  • An alternative to vaccination would be to perform serologic testing for neutralizing antibody to poliovirus types 1, 2, and 3 or give a single dose of IPV, followed by serologic testing. 
 ○ Measles-Mumps-Rubella (MMR) 
  • Immunize with MMR or obtain measles antibody concentration. If positive, give MMR vaccine to protect against mumps and rubella. 
  • An alternative would be to perform serologic testing for IgG antibody to vaccine viruses, indicated by the immunization record. 
 ○ Varicella 
  • Give age-appropriate immunization if there is not a reliable history of previous disease or serologic evidence of disease by varicella antibody. 
 ○ Pneumococcal 
  • Give age-appropriate immunization. 
  • If >12 mo of age, serologic testing for IgG for serotypes 7-14 
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