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TABLE 4

Risk of Pertussis in Children by DTaP Vaccination Status, Overall and by Age Group at KPNC (January 2006–June 2017)

DTaP Vaccination StatusaAge at Follow-up (No. DTaP Doses Corresponding to Fully Vaccinated Status)
Overall: Ages 3–132 mo; 469 982 Children (2 138 835 P-Y) With 738 Pertussis Cases Ages 3 to <5 mo (1 DTaP dose); 348 968 Children (56 792 P-Y) With 30 Pertussis CasesAges 5 to <7 mo (2 DTaP Doses); 43 099 Children (55 939 P-Y) With 22 Pertussis CasesAges 7 to <19 mo (3 DTaP Doses); 357 699 Children (310 259 P-Y) With 110 Pertussis Cases Ages 19 to <84 mo (4 DTaP Doses); 381 578 (Children 1 216 951 P-Y) With 253 Pertussis Cases Ages 84–132 mo (5 DTaP Doses); 172 760 (Children 498 894 P-Y) With 323 Pertussis Cases
aHRb95% CIaHRb95% CIaHRb95% CIaHRb95% CIaHRb95% CIaHRb95% CI
Unvaccinated 13.53 10.64–17.21 4.54 1.62–12.69 15.11 5.02–45.49 12.07 7.23–20.15 23.62 16.32–34.17 8.87 5.00–15.71 
Undervaccinated 1.86 1.32–2.63 — — 4.54 1.20–17.15 1.91 0.91–4.02 2.94 1.78–4.88 0.86 0.38–1.94 
Fully vaccinated plus 1 dose 0.48 0.34–0.68 1.53 0.54–4.36 0.85 0.18–3.98 0.39 0.19–0.80 0.54 0.34–0.87 — — 
DTaP Vaccination StatusaAge at Follow-up (No. DTaP Doses Corresponding to Fully Vaccinated Status)
Overall: Ages 3–132 mo; 469 982 Children (2 138 835 P-Y) With 738 Pertussis Cases Ages 3 to <5 mo (1 DTaP dose); 348 968 Children (56 792 P-Y) With 30 Pertussis CasesAges 5 to <7 mo (2 DTaP Doses); 43 099 Children (55 939 P-Y) With 22 Pertussis CasesAges 7 to <19 mo (3 DTaP Doses); 357 699 Children (310 259 P-Y) With 110 Pertussis Cases Ages 19 to <84 mo (4 DTaP Doses); 381 578 (Children 1 216 951 P-Y) With 253 Pertussis Cases Ages 84–132 mo (5 DTaP Doses); 172 760 (Children 498 894 P-Y) With 323 Pertussis Cases
aHRb95% CIaHRb95% CIaHRb95% CIaHRb95% CIaHRb95% CIaHRb95% CI
Unvaccinated 13.53 10.64–17.21 4.54 1.62–12.69 15.11 5.02–45.49 12.07 7.23–20.15 23.62 16.32–34.17 8.87 5.00–15.71 
Undervaccinated 1.86 1.32–2.63 — — 4.54 1.20–17.15 1.91 0.91–4.02 2.94 1.78–4.88 0.86 0.38–1.94 
Fully vaccinated plus 1 dose 0.48 0.34–0.68 1.53 0.54–4.36 0.85 0.18–3.98 0.39 0.19–0.80 0.54 0.34–0.87 — — 

—, not applicable.

a

Children fully vaccinated according to the ACIP-derived age cut points served as the reference group.

b

aHR adjusted for sex, race or ethnicity, type of insurance, medical clinic, and for age and calendar date because risk sets were defined on a calendar time line and stratified by year and month of birth.

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