Absolute Prevalence of Systemic Drug Orders for Children in US Ambulatory Settings (2006–2015)
| Category . | Orders per 1000 Ambulatory Visits (95% CIs) . | |||||
|---|---|---|---|---|---|---|
| Age <1 mo . | Age 1 mo to <2 y . | Age 2–5 y . | Age 6–11 y . | Age 12–17 y . | All Children . | |
| Any drug | 64.1 (45.3–83.0) | 406.1 (380.2–432.0) | 635.8 (605.3–666.3) | 731.7 (698.1–765.3) | 759.1 (722.9–795.2) | 620.7 (597.2–644.2) |
| Off label, overall | 52.0 (35.7–68.4) | 164.0 (149.3–178.7) | 218.7 (205.0–232.5) | 253.7 (238.2–269.3) | 321.5 (299.9–343.1) | 236.5 (225.1–247.8) |
| Off label by indication | 28.2a (17.5–39.0) | 112.4 (102.1–122.8) | 190.0 (177.7–202.3) | 219.3 (204.8–233.7) | 268.0 (249.0–287.0) | 194.6 (185.0–204.2) |
| Off label by age | 40.8 (26.1–55.5) | 61.4 (53.3–69.6) | 33.5 (28.3–38.6) | 37.6 (32.7–42.5) | 51.2 (44.8–57.7) | 45.9 (42.1–49.8) |
| Category . | Orders per 1000 Ambulatory Visits (95% CIs) . | |||||
|---|---|---|---|---|---|---|
| Age <1 mo . | Age 1 mo to <2 y . | Age 2–5 y . | Age 6–11 y . | Age 12–17 y . | All Children . | |
| Any drug | 64.1 (45.3–83.0) | 406.1 (380.2–432.0) | 635.8 (605.3–666.3) | 731.7 (698.1–765.3) | 759.1 (722.9–795.2) | 620.7 (597.2–644.2) |
| Off label, overall | 52.0 (35.7–68.4) | 164.0 (149.3–178.7) | 218.7 (205.0–232.5) | 253.7 (238.2–269.3) | 321.5 (299.9–343.1) | 236.5 (225.1–247.8) |
| Off label by indication | 28.2a (17.5–39.0) | 112.4 (102.1–122.8) | 190.0 (177.7–202.3) | 219.3 (204.8–233.7) | 268.0 (249.0–287.0) | 194.6 (185.0–204.2) |
| Off label by age | 40.8 (26.1–55.5) | 61.4 (53.3–69.6) | 33.5 (28.3–38.6) | 37.6 (32.7–42.5) | 51.2 (44.8–57.7) | 45.9 (42.1–49.8) |
Values are based on <30 observations.