Characteristics According to CDA
. | CDA at the Age of 6 y . | ||
---|---|---|---|
No CDA (n = 3664) . | CDA (n = 51) . | Pa . | |
Child characteristics | |||
Age at research center visit, median (range), y | 6.0 (4.9−90) | 6.0 (5.6−8.2) | .90 |
Female sex, n (%) | 1755 (47.9) | 33 (64.7) | .02 |
BMI, median (range) | 15.82 (12.04−27.65) | 15.40 (12.99−19.45) | .01 |
Wt, median (range), kg | 23.4 (13.0−56.0) | 21.0 (16.0−35.6) | .00 |
Height, mean (SD), cm | 119.5 (5.9) | 118.0 (6.3) | .07 |
BMI for age SDS, mean (SD) | 0.26 (0.9) | −0.03 (0.8) | .02 |
Birth wt, median (range), g | 3460 (635−5270) | 3520 (1810−4750) | .75 |
HLA-DQ2 and/or HLA-DQ8 positivity (yes), n (%) | 1492 (40.7) | 47 (92.2) | .00 |
Western ethnicity, n (%) | 2533 (69.1) | 42 (82.4) | .04 |
Gastrointestinal complaints (yes), n (%) | |||
Obstipation | 702 (19.2) | 6 (11.8) | .20 |
Diarrhea | 114 (3.1) | 2 (3.9) | .65 |
Abdominal pain | 4S4 (13.2) | 6 (11.8) | .57 |
Maternal characteristics | |||
Income ≥€2200, n (%) | 2173 (59.3) | 38 (74.5) | .05 |
High educational level, n (%) | 1853 (50.6) | 33 (64.7) | .06 |
TG2A titers with positive results during second trimester, n (%) | 12 (0.4) | 1 (2.8) | .04 |
Unknown antibody titers | 896 | 15 | — |
. | CDA at the Age of 6 y . | ||
---|---|---|---|
No CDA (n = 3664) . | CDA (n = 51) . | Pa . | |
Child characteristics | |||
Age at research center visit, median (range), y | 6.0 (4.9−90) | 6.0 (5.6−8.2) | .90 |
Female sex, n (%) | 1755 (47.9) | 33 (64.7) | .02 |
BMI, median (range) | 15.82 (12.04−27.65) | 15.40 (12.99−19.45) | .01 |
Wt, median (range), kg | 23.4 (13.0−56.0) | 21.0 (16.0−35.6) | .00 |
Height, mean (SD), cm | 119.5 (5.9) | 118.0 (6.3) | .07 |
BMI for age SDS, mean (SD) | 0.26 (0.9) | −0.03 (0.8) | .02 |
Birth wt, median (range), g | 3460 (635−5270) | 3520 (1810−4750) | .75 |
HLA-DQ2 and/or HLA-DQ8 positivity (yes), n (%) | 1492 (40.7) | 47 (92.2) | .00 |
Western ethnicity, n (%) | 2533 (69.1) | 42 (82.4) | .04 |
Gastrointestinal complaints (yes), n (%) | |||
Obstipation | 702 (19.2) | 6 (11.8) | .20 |
Diarrhea | 114 (3.1) | 2 (3.9) | .65 |
Abdominal pain | 4S4 (13.2) | 6 (11.8) | .57 |
Maternal characteristics | |||
Income ≥€2200, n (%) | 2173 (59.3) | 38 (74.5) | .05 |
High educational level, n (%) | 1853 (50.6) | 33 (64.7) | .06 |
TG2A titers with positive results during second trimester, n (%) | 12 (0.4) | 1 (2.8) | .04 |
Unknown antibody titers | 896 | 15 | — |
—, not applicable.
Differences in subject characteristics between the groups were evaluated by using t tests and Mann–Whitney U tests for continuous variables and χ2 tests for categorical variables.