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TABLE 3

Association of CDA With CBCL Scores

Adjusted Model 2, β (95% CI)Adjusted Model 3, β (95% CI)aAdjusted Model 4, β (95% CI)b
CBCL syndrome scales    
 Internalizing compositec,d,e,f,g,h .16 (−0.16 to 0.47) .15 (−0.17 to 0.47) .21 (−0.10 to 0.52) 
 Emotionally reactivec,d,e,f,g .22 (−0.06 to 0.49) .21 (−0.07 to 0.49) .23 (−0.04 to 0.51) 
 Anxious and/or depressedd,e,f,g,h .02 (−0.31 to 0.35) .03 (−0.30 to 0.36) .06 (−0.27 to 0.38) 
 Somatic complaintsc,d,e,f .05 (−0.23 to 0.32) .03 (−0.25 to 0.30) .09 (−0.17 to 0.35) 
 Withdrawnc,d,g,h .19 (−0.14 to 0.52) .18 (−0.15 to 0.51) .22 (−0.11 to 0.55) 
 Externalizing compositec,d,e,f,g,h .26 (−0.06 to 0.58) .26 (−0.06 to 0.58) .29 (−0.03 to 0.60) 
 Attention problemsc,d,e,f,g .03 (−0.30 to 0.35) .03 (−0.30 to 0.35) .05 (−0.27 to 0.37) 
 Aggressive behaviorc,d,e,f,g,h .30 (−0.02 to 0.63) .30 (−0.02 to 0.63) .32 (0.00 to 0.65)* 
 Sleep problemsc,d,e,f,g,h .20 (−0.13 to0.53) .21 (−0.12 to 0.54) .24 (−0.09 to 0.56) 
DSM-oriented scales    
 Affectived,f,g,h,i −.07 (−0.40 to 0.26) −.07 (−0.39 to 0.26) −.02 (−0.34 to 0.30) 
 Anxietye,f,g .29 (0.02 to 0.56)** .29 (0.02 to 0.56)** .31 (0.04 to 0.57)*** 
 Pervasive developmentc,d,g,h .16 (−0.17 to 0.49) .16 (−0.17 to 0.49) .19 (−0.14 to 0.52) 
 Attention-deficit/hyperactivityc,d,e,f,g,h,i .24 (−0.08 to 0.57) .25 (−0.07 to 0.57) .26 (−0.06 to 0.58) 
 Oppositional defiant problemsc,d,g,h .33 (0.00 to 0.65)* .33 (0.00 to 0.65)* .35 (0.02 to 0.67)** 
Adjusted Model 2, β (95% CI)Adjusted Model 3, β (95% CI)aAdjusted Model 4, β (95% CI)b
CBCL syndrome scales    
 Internalizing compositec,d,e,f,g,h .16 (−0.16 to 0.47) .15 (−0.17 to 0.47) .21 (−0.10 to 0.52) 
 Emotionally reactivec,d,e,f,g .22 (−0.06 to 0.49) .21 (−0.07 to 0.49) .23 (−0.04 to 0.51) 
 Anxious and/or depressedd,e,f,g,h .02 (−0.31 to 0.35) .03 (−0.30 to 0.36) .06 (−0.27 to 0.38) 
 Somatic complaintsc,d,e,f .05 (−0.23 to 0.32) .03 (−0.25 to 0.30) .09 (−0.17 to 0.35) 
 Withdrawnc,d,g,h .19 (−0.14 to 0.52) .18 (−0.15 to 0.51) .22 (−0.11 to 0.55) 
 Externalizing compositec,d,e,f,g,h .26 (−0.06 to 0.58) .26 (−0.06 to 0.58) .29 (−0.03 to 0.60) 
 Attention problemsc,d,e,f,g .03 (−0.30 to 0.35) .03 (−0.30 to 0.35) .05 (−0.27 to 0.37) 
 Aggressive behaviorc,d,e,f,g,h .30 (−0.02 to 0.63) .30 (−0.02 to 0.63) .32 (0.00 to 0.65)* 
 Sleep problemsc,d,e,f,g,h .20 (−0.13 to0.53) .21 (−0.12 to 0.54) .24 (−0.09 to 0.56) 
DSM-oriented scales    
 Affectived,f,g,h,i −.07 (−0.40 to 0.26) −.07 (−0.39 to 0.26) −.02 (−0.34 to 0.30) 
 Anxietye,f,g .29 (0.02 to 0.56)** .29 (0.02 to 0.56)** .31 (0.04 to 0.57)*** 
 Pervasive developmentc,d,g,h .16 (−0.17 to 0.49) .16 (−0.17 to 0.49) .19 (−0.14 to 0.52) 
 Attention-deficit/hyperactivityc,d,e,f,g,h,i .24 (−0.08 to 0.57) .25 (−0.07 to 0.57) .26 (−0.06 to 0.58) 
 Oppositional defiant problemsc,d,g,h .33 (0.00 to 0.65)* .33 (0.00 to 0.65)* .35 (0.02 to 0.67)** 

Values are regression coefficients (95% CI) from linear regression models that reflect differences in CBCL z scores on the CBCL syndrome scale and DSM-oriented scale according to CDA. Estimates are based on multiple-imputed data.

a

Adjusted for confounders in model 2 and additionally adjusted for BMI.

b

Adjusted for confounders in model 2 and additionally adjusted for gastrointestinal complaints.

c

Adjusted for sex.

d

Adjusted for HLA antigen type.

e

Adjusted for ethnicity.

f

Adjusted for maternal income.

g

Adjusted for maternal education level.

h

Adjusted for maternal antibody level.

i

Adjusted for birth wt.

*

P = .05;

**

P = .02;

***

P = .01.

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