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TABLE 1

Demographic, Clinical, and Laboratory Characteristics of Children With Third-Generation Cephalosporin-Resistant UTIs Started on Discordant Antibiotic Therapy

N = 316
Sex, n (%)  
 Male 69 (21.8) 
 Female 247 (78.2) 
Age, median (IQR) 2.4 (0.6–6.5) 
Age category, n (%)  
 <2 mo 24 (7.6) 
 2–23 mo 123 (38.9) 
 2–4 y 65 (20.6) 
 5–17 y 104 (32.9) 
History of VUR or renal abnormalities, n (%) 16 (5.1) 
Previous UTI, n (%) 65 (20.6) 
Previous third-generation cephalosporin-resistant UTI, n (%) 3 (1.0) 
Setting of initial evaluation, n (%)  
 General pediatrics or urgent care clinic 137 (43.4) 
 ED 178 (56.3) 
 Inpatient 1 (0.3) 
Ill appearance, n (%) 8 (2.5) 
Presenting symptoms, n (%)  
 Fever 201 (63.6) 
 Nausea and/or vomiting 73 (23.1) 
 Poor oral intake 64 (20.3) 
 Fussiness and/or irritability 39 (12.3) 
 Abdominal and/or back pain 52 (16.4) 
 Dysuria 113 (35.8) 
 Abnormal urine odor 48 (15.2) 
Urine culture organism, n (%)  
E coli 312 (98.7) 
Klebsiella spp. 4 (1.3) 
Urine culture colony count, n (%)  
 50 000–100 000 CFU/mL 48 (15.2) 
 >100 000 CFU/mL 268 (84.8) 
Urine culture collection method, n (%)  
 Straight catheterization 134 (42.4) 
 Clean catch 164 (51.9) 
 Not documented 18 (5.7) 
Hospitalized on initial presentation, n (%) 44 (13.9) 
Method of follow-up, n (%)  
 Phone follow-up 226 (71.8) 
 Outpatient or ED visit 25 (7.9) 
 Inpatient admission 64 (20.3) 
Clinical response information available at the time of follow-up, n (%) 230 (72.8) 
N = 316
Sex, n (%)  
 Male 69 (21.8) 
 Female 247 (78.2) 
Age, median (IQR) 2.4 (0.6–6.5) 
Age category, n (%)  
 <2 mo 24 (7.6) 
 2–23 mo 123 (38.9) 
 2–4 y 65 (20.6) 
 5–17 y 104 (32.9) 
History of VUR or renal abnormalities, n (%) 16 (5.1) 
Previous UTI, n (%) 65 (20.6) 
Previous third-generation cephalosporin-resistant UTI, n (%) 3 (1.0) 
Setting of initial evaluation, n (%)  
 General pediatrics or urgent care clinic 137 (43.4) 
 ED 178 (56.3) 
 Inpatient 1 (0.3) 
Ill appearance, n (%) 8 (2.5) 
Presenting symptoms, n (%)  
 Fever 201 (63.6) 
 Nausea and/or vomiting 73 (23.1) 
 Poor oral intake 64 (20.3) 
 Fussiness and/or irritability 39 (12.3) 
 Abdominal and/or back pain 52 (16.4) 
 Dysuria 113 (35.8) 
 Abnormal urine odor 48 (15.2) 
Urine culture organism, n (%)  
E coli 312 (98.7) 
Klebsiella spp. 4 (1.3) 
Urine culture colony count, n (%)  
 50 000–100 000 CFU/mL 48 (15.2) 
 >100 000 CFU/mL 268 (84.8) 
Urine culture collection method, n (%)  
 Straight catheterization 134 (42.4) 
 Clean catch 164 (51.9) 
 Not documented 18 (5.7) 
Hospitalized on initial presentation, n (%) 44 (13.9) 
Method of follow-up, n (%)  
 Phone follow-up 226 (71.8) 
 Outpatient or ED visit 25 (7.9) 
 Inpatient admission 64 (20.3) 
Clinical response information available at the time of follow-up, n (%) 230 (72.8) 

VUR, vesicoureteral reflux.

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