Demographic and Clinical Differences Between Infectious and Autoimmune Encephalitis
Etiology . | Infectious Encephalitis (n = 73), /n (%) . | Autoimmune Encephalitis (n = 60), n (%) . | P . | OR (95% CI) . |
---|---|---|---|---|
Male sex | 48 (66) | 25 (42) | .005 | 2.7 (1.3–5.8) |
Age 8 y or older | 28 (38) | 32 (53) | .08 | 0.54 (0.3–1.2) |
Race or ethnicity other than white, non-Hispanic | 42 (58) | 44 (73) | .06 | 0.49 (0.2–1.1) |
Immune compromiseda | 12 (16) | 2 (3) | .02 | 5.7 (1.2–54.1) |
New onset seizure | 45 (62) | 39 (65) | .07 | 0.87 (0.4–1.9) |
Abnormal MRI | 53 out of 68 (78) | 33 out of 59 (56) | .008 | 2.8 (1.2–6.5) |
Abnormal EEG | 47 out of 53 (89) | 33 out of 42 (79) | .18 | 2.1 (0.6–8.0) |
Hospitalized 7 d or longer | 56 (77) | 54 (90) | .04 | 0.37 (0.1–1.1) |
Etiology . | Infectious Encephalitis (n = 73), /n (%) . | Autoimmune Encephalitis (n = 60), n (%) . | P . | OR (95% CI) . |
---|---|---|---|---|
Male sex | 48 (66) | 25 (42) | .005 | 2.7 (1.3–5.8) |
Age 8 y or older | 28 (38) | 32 (53) | .08 | 0.54 (0.3–1.2) |
Race or ethnicity other than white, non-Hispanic | 42 (58) | 44 (73) | .06 | 0.49 (0.2–1.1) |
Immune compromiseda | 12 (16) | 2 (3) | .02 | 5.7 (1.2–54.1) |
New onset seizure | 45 (62) | 39 (65) | .07 | 0.87 (0.4–1.9) |
Abnormal MRI | 53 out of 68 (78) | 33 out of 59 (56) | .008 | 2.8 (1.2–6.5) |
Abnormal EEG | 47 out of 53 (89) | 33 out of 42 (79) | .18 | 2.1 (0.6–8.0) |
Hospitalized 7 d or longer | 56 (77) | 54 (90) | .04 | 0.37 (0.1–1.1) |
Cell value <5, so Fisher exact was used to calculate 2-tailed P value.