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TABLE 1

Alkylating Agents With Infertility Risk

Alkylating Agents
Classic alkylating agents 
 Busulfan 
 Carmustine (BCNU) 
 Chlorambucil 
 Cyclophosphamide 
 Ifosfamide 
 Lomustine (CCNU) 
 Mechlorethamine 
 Melphalan 
 Procarbazine 
 Thiotepa 
Heavy metals 
 Cisplatinum 
 Carboplatinum 
Nonclassical alkylators 
 Dacarbazine (DTIC) 
 Temozolomide 
Alkylating Agents
Classic alkylating agents 
 Busulfan 
 Carmustine (BCNU) 
 Chlorambucil 
 Cyclophosphamide 
 Ifosfamide 
 Lomustine (CCNU) 
 Mechlorethamine 
 Melphalan 
 Procarbazine 
 Thiotepa 
Heavy metals 
 Cisplatinum 
 Carboplatinum 
Nonclassical alkylators 
 Dacarbazine (DTIC) 
 Temozolomide 

Adapted from Children’s Oncology Group. Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers. Version 5.0. Monrovia, CA: Children’s Oncology Group; 2018:12–14. Available at: http://www.survivorshipguidelines.org/pdf/2018/COG_LTFU_Guidelines_v5.pdf. Accessed April 26, 2019.

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