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TABLE 1

Risk of ADHD Medication Use Among Boys Born 2005–2007 by Birth Month

200520062007
PersonsCases With ADHD Medication, n (%)HR (95% CI)PersonsCases With ADHD Medication, n (%)HR (95% CI)PersonsCases With ADHD Medication, n (%)HR (95% CI)
Total 30 580 1967 (6.4) — 31 414 1941 (6.2) — 31 380 1867 (5.9) — 
Follow-up on December 31, 2017          
 January to April (ref) 9911 529 (5.3) 10 500 572 (5.4) 10 350 548 (5.3) 
 May to August 10 638 705 (6.6) 1.24*** (1.10–1.40) 10 822 665 (6.1) 1.13* (1.01–1.27) 10 927 652 (6.0) 1.13* (1.01–1.27) 
 September to December 10 031 733 (7.3) 1.39*** (1.24–1.54) 10 092 704 (7.0) 1.29*** (1.16–1.45) 10 103 666 (6.6) 1.26***(1.12–1.41) 
Follow-up at the end of the year of eighth birthday          
 January to April (ref) 9911 225 (2.3) 10 500 306 (2.9) 10 350 322 (3.1) 
 May to August 10 638 350 (3.3) 1.27** (1.07–1.50) 10 822 362 (3.3) 1.15 (0.99–1.34) 10 927 422 (3.9) 1.25** (1.08–1.44) 
 September to December 10 031 407 (4.4) 1.67*** (1.42–1.97) 10 092 423 (4.2) 1.45*** (1.25–1.68) 10 103 472 (4.7) 1.51*** (1.31–1.74) 
200520062007
PersonsCases With ADHD Medication, n (%)HR (95% CI)PersonsCases With ADHD Medication, n (%)HR (95% CI)PersonsCases With ADHD Medication, n (%)HR (95% CI)
Total 30 580 1967 (6.4) — 31 414 1941 (6.2) — 31 380 1867 (5.9) — 
Follow-up on December 31, 2017          
 January to April (ref) 9911 529 (5.3) 10 500 572 (5.4) 10 350 548 (5.3) 
 May to August 10 638 705 (6.6) 1.24*** (1.10–1.40) 10 822 665 (6.1) 1.13* (1.01–1.27) 10 927 652 (6.0) 1.13* (1.01–1.27) 
 September to December 10 031 733 (7.3) 1.39*** (1.24–1.54) 10 092 704 (7.0) 1.29*** (1.16–1.45) 10 103 666 (6.6) 1.26***(1.12–1.41) 
Follow-up at the end of the year of eighth birthday          
 January to April (ref) 9911 225 (2.3) 10 500 306 (2.9) 10 350 322 (3.1) 
 May to August 10 638 350 (3.3) 1.27** (1.07–1.50) 10 822 362 (3.3) 1.15 (0.99–1.34) 10 927 422 (3.9) 1.25** (1.08–1.44) 
 September to December 10 031 407 (4.4) 1.67*** (1.42–1.97) 10 092 423 (4.2) 1.45*** (1.25–1.68) 10 103 472 (4.7) 1.51*** (1.31–1.74) 

Cox proportional hazards regression model. Cases include all the children who had ≥1 reimbursed purchase of ADHD medication by the end of follow-up (% = cumulative incidence). CI, confidence interval; ref, reference category; —, not applicable.

***

P ≤ .001

**

P ≤ .01

*

P ≤ .05.

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