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TABLE 2

Risk of ADHD Medication Use Among Girls Born 2005–2007 by Birth Month

200520062007
PersonsNo. Cases With ADHD Medication (%)HR (95% CI)PersonsNo. Cases With ADHD Medication (%)HR (95% CI)PersonsNo. Cases With ADHD Medication (%)HR (95% CI)
Total 29 528 459 (1.6) — 30 060 401 (1.3) — 29 840 419 (1.4) — 
Follow-up at December 31, 2017          
 January to April (ref) 9753 122 (1.3) 10 004 99 (1.0) 9979 98 (1.0) 
 May to August 10 177 165 (1.6) 1.30* (1.03–1.64) 10 306 149 (1.4) 1.47** (1.14–1.89) 10 205 160 (1.6) 1.60*** (1.25–2.06) 
 September to December 9598 172 (1.8) 1.44** (1.14–1.81) 9750 153 (1.6) 1.59*** (1.24–2.05) 9656 161 (1.7) 1.71*** (1.33–2.19) 
Follow-up at the end of year of eighth birthday          
 January to April (ref) 9753 41 (0.4) 10 004 43 (0.4) 9979 55 (0.6) 
 May to August 10 177 72 (0.7) 1.69** (1.15–2.47) 10 306 82 (0.8) 1.85*** (1.28–2.68) 10 205 96 (0.9) 1.71** (1.23–2.38) 
 September to December 9598 81 (0.8) 2.01*** (1.38–2.93) 9750 87 (0.9) 2.08*** (1.44–3.00) 9656 107 (1.1) 2.02*** (1.46–2.79) 
200520062007
PersonsNo. Cases With ADHD Medication (%)HR (95% CI)PersonsNo. Cases With ADHD Medication (%)HR (95% CI)PersonsNo. Cases With ADHD Medication (%)HR (95% CI)
Total 29 528 459 (1.6) — 30 060 401 (1.3) — 29 840 419 (1.4) — 
Follow-up at December 31, 2017          
 January to April (ref) 9753 122 (1.3) 10 004 99 (1.0) 9979 98 (1.0) 
 May to August 10 177 165 (1.6) 1.30* (1.03–1.64) 10 306 149 (1.4) 1.47** (1.14–1.89) 10 205 160 (1.6) 1.60*** (1.25–2.06) 
 September to December 9598 172 (1.8) 1.44** (1.14–1.81) 9750 153 (1.6) 1.59*** (1.24–2.05) 9656 161 (1.7) 1.71*** (1.33–2.19) 
Follow-up at the end of year of eighth birthday          
 January to April (ref) 9753 41 (0.4) 10 004 43 (0.4) 9979 55 (0.6) 
 May to August 10 177 72 (0.7) 1.69** (1.15–2.47) 10 306 82 (0.8) 1.85*** (1.28–2.68) 10 205 96 (0.9) 1.71** (1.23–2.38) 
 September to December 9598 81 (0.8) 2.01*** (1.38–2.93) 9750 87 (0.9) 2.08*** (1.44–3.00) 9656 107 (1.1) 2.02*** (1.46–2.79) 

Cox proportional hazards regression model. Cases include all the children who had ≥1 reimbursed purchase of ADHD medication by the end of follow-up (% = cumulative incidence). CI, confidence interval; ref, reference category; —, not applicable.

***

P ≤ .001

**

P ≤ .01

*

P ≤ .05.

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