Quick Reference Guide for Blood Tests to Accurately Detect Type-Specific HSV Antibodies
| . | Biokit HSV-2 Rapid Test (also sold as SureVue HSV-2 Rapid Test by Fisher HealthCare) . | BioPlex HSV . | Captia ELISA . | Euroimmun Anti-HSV-1 and Anti-HSV-2 ELISA . | HerpeSelect HSV-1 ELISA and HerpeSelect HSV-2 ELISA . | HerpeSelect 1 and 2 Differentiation Immunoblot . | Liaison HSV-2 . | AtheNA MultiLyte . |
|---|---|---|---|---|---|---|---|---|
| Supplier | Biokit USA | Bio-Rad Laboratories | Trinity Biotech USA | Euroimmun US LLC | Focus Diagnostics | Focus Diagnostics | DiaSorin Inc. | Inverness Medical |
| FDA approved | 1999 | 2009 | 2004 | 2007 | 2000/2002 | 2000 | 2008 | 2008 |
| Antibodies detected | HSV-2 only | HSV-1 or HSV-2 or both | HSV-1 or HSV-2 or both | HSV-1 or HSV-2 | HSV-1 or HSV-2 or both | HSV-1 and/or HSV-2 | HSV-1 or HSV-2 | HSV-1 and/or HSV-2 |
| Best use of test | POC test to screen or test individuals >3 mo postexposure | Screening or testing (high volume) | Screening or testing pregnant women or STD clinic patients (moderate volume) | Moderate volume | Screening or testing STD patients or pregnant women (moderate volume) | Low volume | High volume | Screening or testing (moderate to high volume) |
| Collection method | Finger stick, whole blood, or serum in clinic | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) |
| Test time | 10 min | 45 min | ∼2 h | ∼2 h | ∼2 h | ∼2 h | 35 min | ∼2 h |
| FDA approved for use during pregnancy | Yes | Yes | Yes | Yes | ||||
| Test availability | Limited | Limited | Widely available | Widely available | ||||
| Web site | www.biokitusa.com | www.bio-rad.com | www.trinitybiotech.com | www.euroimmunus.com | www.herpeselect.com | www.herpeselect.com | www.diasorin.com | www.invernessmedicalpd.com |
| For more information | 800-926-3353 | 800-224-6723 | 800-325-3424 | 800-913-2022 | 800-328-5669 | 877-546-8633 |
| . | Biokit HSV-2 Rapid Test (also sold as SureVue HSV-2 Rapid Test by Fisher HealthCare) . | BioPlex HSV . | Captia ELISA . | Euroimmun Anti-HSV-1 and Anti-HSV-2 ELISA . | HerpeSelect HSV-1 ELISA and HerpeSelect HSV-2 ELISA . | HerpeSelect 1 and 2 Differentiation Immunoblot . | Liaison HSV-2 . | AtheNA MultiLyte . |
|---|---|---|---|---|---|---|---|---|
| Supplier | Biokit USA | Bio-Rad Laboratories | Trinity Biotech USA | Euroimmun US LLC | Focus Diagnostics | Focus Diagnostics | DiaSorin Inc. | Inverness Medical |
| FDA approved | 1999 | 2009 | 2004 | 2007 | 2000/2002 | 2000 | 2008 | 2008 |
| Antibodies detected | HSV-2 only | HSV-1 or HSV-2 or both | HSV-1 or HSV-2 or both | HSV-1 or HSV-2 | HSV-1 or HSV-2 or both | HSV-1 and/or HSV-2 | HSV-1 or HSV-2 | HSV-1 and/or HSV-2 |
| Best use of test | POC test to screen or test individuals >3 mo postexposure | Screening or testing (high volume) | Screening or testing pregnant women or STD clinic patients (moderate volume) | Moderate volume | Screening or testing STD patients or pregnant women (moderate volume) | Low volume | High volume | Screening or testing (moderate to high volume) |
| Collection method | Finger stick, whole blood, or serum in clinic | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) | Blood draw (sent to laboratory) |
| Test time | 10 min | 45 min | ∼2 h | ∼2 h | ∼2 h | ∼2 h | 35 min | ∼2 h |
| FDA approved for use during pregnancy | Yes | Yes | Yes | Yes | ||||
| Test availability | Limited | Limited | Widely available | Widely available | ||||
| Web site | www.biokitusa.com | www.bio-rad.com | www.trinitybiotech.com | www.euroimmunus.com | www.herpeselect.com | www.herpeselect.com | www.diasorin.com | www.invernessmedicalpd.com |
| For more information | 800-926-3353 | 800-224-6723 | 800-325-3424 | 800-913-2022 | 800-328-5669 | 877-546-8633 |
FDA, US Food and Drug Administration; POC, point of care; STD, sexually transmitted disease. Adapted from http://www.ashastd.org/. Accessed August 5, 2010.