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TABLE 1

Quick Reference Guide for Blood Tests to Accurately Detect Type-Specific HSV Antibodies

Biokit HSV-2 Rapid Test (also sold as SureVue HSV-2 Rapid Test by Fisher HealthCare)BioPlex HSVCaptia ELISAEuroimmun Anti-HSV-1 and Anti-HSV-2 ELISAHerpeSelect HSV-1 ELISA and HerpeSelect HSV-2 ELISAHerpeSelect 1 and 2 Differentiation ImmunoblotLiaison HSV-2AtheNA MultiLyte
Supplier Biokit USA Bio-Rad Laboratories Trinity Biotech USA Euroimmun US LLC Focus Diagnostics Focus Diagnostics DiaSorin Inc. Inverness Medical 
FDA approved 1999 2009 2004 2007 2000/2002 2000 2008 2008 
Antibodies detected HSV-2 only HSV-1 or HSV-2 or both HSV-1 or HSV-2 or both HSV-1 or HSV-2 HSV-1 or HSV-2 or both HSV-1 and/or HSV-2 HSV-1 or HSV-2 HSV-1 and/or HSV-2 
Best use of test POC test to screen or test individuals >3 mo postexposure Screening or testing (high volume) Screening or testing pregnant women or STD clinic patients (moderate volume) Moderate volume Screening or testing STD patients or pregnant women (moderate volume) Low volume High volume Screening or testing (moderate to high volume) 
Collection method Finger stick, whole blood, or serum in clinic Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) 
Test time 10 min 45 min ∼2 h ∼2 h ∼2 h ∼2 h 35 min ∼2 h 
FDA approved for use during pregnancy  Yes Yes  Yes Yes   
Test availability Limited Limited Widely available  Widely available    
Web site www.biokitusa.com www.bio-rad.com www.trinitybiotech.com www.euroimmunus.com www.herpeselect.com www.herpeselect.com www.diasorin.com www.invernessmedicalpd.com 
For more information 800-926-3353 800-224-6723 800-325-3424 800-913-2022   800-328-5669 877-546-8633 
Biokit HSV-2 Rapid Test (also sold as SureVue HSV-2 Rapid Test by Fisher HealthCare)BioPlex HSVCaptia ELISAEuroimmun Anti-HSV-1 and Anti-HSV-2 ELISAHerpeSelect HSV-1 ELISA and HerpeSelect HSV-2 ELISAHerpeSelect 1 and 2 Differentiation ImmunoblotLiaison HSV-2AtheNA MultiLyte
Supplier Biokit USA Bio-Rad Laboratories Trinity Biotech USA Euroimmun US LLC Focus Diagnostics Focus Diagnostics DiaSorin Inc. Inverness Medical 
FDA approved 1999 2009 2004 2007 2000/2002 2000 2008 2008 
Antibodies detected HSV-2 only HSV-1 or HSV-2 or both HSV-1 or HSV-2 or both HSV-1 or HSV-2 HSV-1 or HSV-2 or both HSV-1 and/or HSV-2 HSV-1 or HSV-2 HSV-1 and/or HSV-2 
Best use of test POC test to screen or test individuals >3 mo postexposure Screening or testing (high volume) Screening or testing pregnant women or STD clinic patients (moderate volume) Moderate volume Screening or testing STD patients or pregnant women (moderate volume) Low volume High volume Screening or testing (moderate to high volume) 
Collection method Finger stick, whole blood, or serum in clinic Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) Blood draw (sent to laboratory) 
Test time 10 min 45 min ∼2 h ∼2 h ∼2 h ∼2 h 35 min ∼2 h 
FDA approved for use during pregnancy  Yes Yes  Yes Yes   
Test availability Limited Limited Widely available  Widely available    
Web site www.biokitusa.com www.bio-rad.com www.trinitybiotech.com www.euroimmunus.com www.herpeselect.com www.herpeselect.com www.diasorin.com www.invernessmedicalpd.com 
For more information 800-926-3353 800-224-6723 800-325-3424 800-913-2022   800-328-5669 877-546-8633 

FDA, US Food and Drug Administration; POC, point of care; STD, sexually transmitted disease. Adapted from http://www.ashastd.org/. Accessed August 5, 2010.

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