| Aggregate Evidence Quality . | Grade D . |
|---|---|
| Benefits | Avoidance of complications of an invasive procedure (angiography) |
| Risks, harm, cost | Potential false-positive or false-negative results |
| Benefit–harm assessment | Potential for avoidance of an invasive procedure outweighs risk of false-negative or false-positive results |
| Intentional vagueness | None |
| Role of patient preferences | None |
| Exclusions | Children and adolescents without suspected RAS |
| Strength | Weak recommendation; pediatric data are limited |
| Key references | 389,390 |
| Aggregate Evidence Quality . | Grade D . |
|---|---|
| Benefits | Avoidance of complications of an invasive procedure (angiography) |
| Risks, harm, cost | Potential false-positive or false-negative results |
| Benefit–harm assessment | Potential for avoidance of an invasive procedure outweighs risk of false-negative or false-positive results |
| Intentional vagueness | None |
| Role of patient preferences | None |
| Exclusions | Children and adolescents without suspected RAS |
| Strength | Weak recommendation; pediatric data are limited |
| Key references | 389,390 |