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Aggregate Evidence QualityGrade B
Benefits Potential prevention of progressive CVD; regression or avoidance of target organ damage; resolution of hypertensive symptoms; improved cognition; avoidance of worsening HTN; potential avoidance of stroke, heart failure, coronary artery disease, kidney failure 
Risks, harm, cost Potential for hypotension, financial cost, chronic medication treatment, adverse medication effects, impact on insurability (health and life) 
Benefit–harm assessment Preponderance of benefits over harms 
Intentional vagueness None 
Role of patient preferences The choice of which antihypertensive medication to use should be made in close discussion with the patient and parent regarding risk, benefits, and adverse effects 
Exclusions None 
Strength Moderate recommendation 
Key references 452,455,467  
Aggregate Evidence QualityGrade B
Benefits Potential prevention of progressive CVD; regression or avoidance of target organ damage; resolution of hypertensive symptoms; improved cognition; avoidance of worsening HTN; potential avoidance of stroke, heart failure, coronary artery disease, kidney failure 
Risks, harm, cost Potential for hypotension, financial cost, chronic medication treatment, adverse medication effects, impact on insurability (health and life) 
Benefit–harm assessment Preponderance of benefits over harms 
Intentional vagueness None 
Role of patient preferences The choice of which antihypertensive medication to use should be made in close discussion with the patient and parent regarding risk, benefits, and adverse effects 
Exclusions None 
Strength Moderate recommendation 
Key references 452,455,467  
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