Skip to Main Content
TABLE 1

Baseline Characteristics and Trial Outcomes by Treatment Group, per Protocol (N = 676)

Baseline CharacteristicsCPAP (n = 338)Nasal HF (n = 338)P
Gestational age at trial entry    
 Weeks, mean (SD) 36.8 (2.9) 36.9 (2.8) .67 
  <34 wk, n (%) 64 (19) 64 (19) 1.00 
 Birth wt, mean (SD), g 2846 (781) 2930 (789) .17 
 Female sex, n (%) 122 (36) 125 (37) .81 
 Multiple births, n (%) 35 (10) 25 (7) .18 
 Received prerandomization CPAP, n (%) 69 (20) 51 (15) .11 
 Duration, mean (range),a min 52 (5–115) 63 (10–120) .08 
Trial outcome, n (%)    
 Treatment failure within 72 h 27 (8) 49 (14) .007 
 Intubation anytime during admission 20 (6) 26 (8) .36 
 Transfer to NICU anytime during admission 31 (9) 29 (9) .79 
 Down transfersb 42 (12) 41 (12) .91 
Beyond trial and up to 12 mo, n (%)    
 Infants with subsequent special care nursery hospitalizationsc 65 (19) 59 (17) .55 
Baseline CharacteristicsCPAP (n = 338)Nasal HF (n = 338)P
Gestational age at trial entry    
 Weeks, mean (SD) 36.8 (2.9) 36.9 (2.8) .67 
  <34 wk, n (%) 64 (19) 64 (19) 1.00 
 Birth wt, mean (SD), g 2846 (781) 2930 (789) .17 
 Female sex, n (%) 122 (36) 125 (37) .81 
 Multiple births, n (%) 35 (10) 25 (7) .18 
 Received prerandomization CPAP, n (%) 69 (20) 51 (15) .11 
 Duration, mean (range),a min 52 (5–115) 63 (10–120) .08 
Trial outcome, n (%)    
 Treatment failure within 72 h 27 (8) 49 (14) .007 
 Intubation anytime during admission 20 (6) 26 (8) .36 
 Transfer to NICU anytime during admission 31 (9) 29 (9) .79 
 Down transfersb 42 (12) 41 (12) .91 
Beyond trial and up to 12 mo, n (%)    
 Infants with subsequent special care nursery hospitalizationsc 65 (19) 59 (17) .55 

Student's t test for continuous outcomes and χ2 tests for dichotomous outcomes were used.

a

For infants who received prerandomization CPAP only.

b

Down transfers (transfers to same or lower level nontertiary special care nursery) occurred for reasons such as closer to home and seeking private care. The reported figure reflects sum of down transfers including back transfers from NICUs to nontertiary nurseries and transfers from participating hospitals to similar or lower level nurseries.

c

Subsequent special care nursery hospitalizations are defined as hospitalizations occurring after infants were first discharged from the hospital. More details including the reasons for hospital resource use in subsequent hospitalizations are described in the Supplemental Information 3.

Close Modal

or Create an Account

Close Modal
Close Modal