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TABLE 1

Patient Characteristics and Their Effect on Hospital Discharge Among Children in the Medical Conditions and ICU Cohorts, FluSurv-NET

VariableMedical Conditions Cohort (n = 309)ICU Cohort (n = 299)
TotalNo. (%) with characteristicHRPTotalNo. (%) with characteristicHRP
Age category, y         
 <1 309 57 (18) 1.13 .39 299 74 (25) 0.94 .45 
 1–4 309 94 (30) 1.19 n/a 299 115 (38) 1.11 n/a 
 5–17 309 158 (51) ref n/a 299 110 (37) ref n/a 
Male sex 309 164 (53) 1.03 .78 299 162 (54) 1.00 .99 
Race and ethnicity         
 Hispanic 309 57 (18) 1.10 .65 299 62 (21) 0.99 >.99 
 White, non-Hispanic 309 96 (31) 0.96 n/a 299 104 (35) 1.01 n/a 
 Black, non-Hispanic 309 110 (36) 1.14 n/a 299 87 (29) 1.00 n/a 
 Other, non-Hispanic (including race unknown) 309 46 (15) ref n/a 299 46 (15) ref n/a 
Underlying medical condition         
 Any 309 309 (100) n/a n/a 286 206 (72) 0.85 .21 
 Asthma or reactive airways disease 309 77 (25) 0.81 .11 299 87 (29) 0.92 .52 
 Chronic lung disease 309 45 (15) 0.59a <.01a 299 37 (12) 0.90 .38 
 Cardiovascular disease 309 47 (15) 0.84 .27 299 25 (8) 0.78 .26 
 Neurologic or neuromuscular 309 104 (34) 0.93 .53 299 90 (30) 0.77a .01a 
 Immunocompromised condition 309 62 (20) 0.95 .69 299 16 (5) 0.72a .05a 
 Prematurityb 113 37 (33) 0.89 .58 47 21 (45) 0.77 .37 
 Otherc 309 176 (57) 1.10 .43 299 53 (18) 0.67a <.01a 
Received current season influenza vaccination 296 143 (48) 0.88 .29 186 68 (37) 0.98 .87 
Reason for current hospital admission (per medical record)         
 Acute respiratory illnessd 309 230 (74) 1.05 .71 299 210 (70) 0.92 .51 
 Asthma and/or COPD exacerbation 309 14 (5) 0.85 .55 299 38 (13) 1.19 .29 
 Pneumonia 309 5 (2) 0.69 .40 299 18 (6) 1.17 .26 
 Other respiratory or cardiac condition 309 37 (12) 1.07 .71 299 69 (23) 0.96 .76 
 Fever alone 309 38 (12) 1.18 .35 299 22 (7) 1.30 .13 
Initial admission to ICU n/a n/a n/a 289 247 (85) 1.39a <.01a 
VariableMedical Conditions Cohort (n = 309)ICU Cohort (n = 299)
TotalNo. (%) with characteristicHRPTotalNo. (%) with characteristicHRP
Age category, y         
 <1 309 57 (18) 1.13 .39 299 74 (25) 0.94 .45 
 1–4 309 94 (30) 1.19 n/a 299 115 (38) 1.11 n/a 
 5–17 309 158 (51) ref n/a 299 110 (37) ref n/a 
Male sex 309 164 (53) 1.03 .78 299 162 (54) 1.00 .99 
Race and ethnicity         
 Hispanic 309 57 (18) 1.10 .65 299 62 (21) 0.99 >.99 
 White, non-Hispanic 309 96 (31) 0.96 n/a 299 104 (35) 1.01 n/a 
 Black, non-Hispanic 309 110 (36) 1.14 n/a 299 87 (29) 1.00 n/a 
 Other, non-Hispanic (including race unknown) 309 46 (15) ref n/a 299 46 (15) ref n/a 
Underlying medical condition         
 Any 309 309 (100) n/a n/a 286 206 (72) 0.85 .21 
 Asthma or reactive airways disease 309 77 (25) 0.81 .11 299 87 (29) 0.92 .52 
 Chronic lung disease 309 45 (15) 0.59a <.01a 299 37 (12) 0.90 .38 
 Cardiovascular disease 309 47 (15) 0.84 .27 299 25 (8) 0.78 .26 
 Neurologic or neuromuscular 309 104 (34) 0.93 .53 299 90 (30) 0.77a .01a 
 Immunocompromised condition 309 62 (20) 0.95 .69 299 16 (5) 0.72a .05a 
 Prematurityb 113 37 (33) 0.89 .58 47 21 (45) 0.77 .37 
 Otherc 309 176 (57) 1.10 .43 299 53 (18) 0.67a <.01a 
Received current season influenza vaccination 296 143 (48) 0.88 .29 186 68 (37) 0.98 .87 
Reason for current hospital admission (per medical record)         
 Acute respiratory illnessd 309 230 (74) 1.05 .71 299 210 (70) 0.92 .51 
 Asthma and/or COPD exacerbation 309 14 (5) 0.85 .55 299 38 (13) 1.19 .29 
 Pneumonia 309 5 (2) 0.69 .40 299 18 (6) 1.17 .26 
 Other respiratory or cardiac condition 309 37 (12) 1.07 .71 299 69 (23) 0.96 .76 
 Fever alone 309 38 (12) 1.18 .35 299 22 (7) 1.30 .13 
Initial admission to ICU n/a n/a n/a 289 247 (85) 1.39a <.01a 

Total denotes number of nonmissing values; HRs were determined by using a single-variable Cox model; HRs <1 indicate a lower risk of discharge and longer length of hospital stay and vice versa. COPD, chronic obstructive pulmonary disease; n/a, not applicable; ref, reference category.

a

Denotes a statistically significant result.

b

Recorded only for children <2 y old.

c

Includes chronic metabolic disease, blood disorder, and renal and liver disease.

d

Per the case report form instructions, acute respiratory illness was defined as bronchitis, cough, influenza, influenza-like disease, upper respiratory infection, respiratory infection, rhinorrhea or runny nose, viral syndrome, viral upper respiratory illness, or fever and any of the previously listed symptoms.

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